Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs

Brice M.R. Appenzeller; Aristidis M. Tsatsakis

doi:10.1016/j.toxlet.2011.10.021

Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs

Brice M.R. Appenzeller^*, Aristidis M. Tsatsakis

^*Corresponding author for this work

Human Biomonitoring Research Unit

Research output: Contribution to journal › Review article › peer-review

158 Citations (Scopus)

Abstract

This paper presents the current state of the art in human hair analysis for the detection of organic pollutants associated with environmental and occupational exposure. The different chemical classes are reviewed with a special focus set on compounds that were only recently investigated. The importance of methods sensitivity and particularly the influence of this parameter on the results presented in previous publications is highlighted. This report also investigates the relevance of hair analysis as an indicator of subjects' level of exposure and underlines limitations that are still associated with this matrix. This study also presents a critical assessment of some specific aspects presented in the literature as well as future needs to strengthen the position of hair as a relevant biomarker of exposure to be used in epidemiological studies.

Original language	English
Pages (from-to)	119-140
Number of pages	22
Journal	Toxicology Letters
Volume	210
Issue number	2
DOIs	https://doi.org/10.1016/j.toxlet.2011.10.021
Publication status	Published - 25 Apr 2012

Keywords

Biomarker of exposure
Hair analysis
Human biomonitoring
Organic pollutants

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10.1016/j.toxlet.2011.10.021

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title = "Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs",

abstract = "This paper presents the current state of the art in human hair analysis for the detection of organic pollutants associated with environmental and occupational exposure. The different chemical classes are reviewed with a special focus set on compounds that were only recently investigated. The importance of methods sensitivity and particularly the influence of this parameter on the results presented in previous publications is highlighted. This report also investigates the relevance of hair analysis as an indicator of subjects' level of exposure and underlines limitations that are still associated with this matrix. This study also presents a critical assessment of some specific aspects presented in the literature as well as future needs to strengthen the position of hair as a relevant biomarker of exposure to be used in epidemiological studies.",

keywords = "Biomarker of exposure, Hair analysis, Human biomonitoring, Organic pollutants",

author = "Appenzeller, {Brice M.R.} and Tsatsakis, {Aristidis M.}",

note = "Funding Information: This work was supported in part by the French Agency for Food, Environmental and Occupational Health Safety (ANSES), in the framework of the Pesticide Residue Observatory action and by the Luxembourg Minist{\`e}re de l{\textquoteright}Education Sup{\'e}rieure et de la Recherche. The authors wish to warmly thank Laetitia Bragard for her logistic support, without which this study would not have been possible.",

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doi = "10.1016/j.toxlet.2011.10.021",

language = "English",

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journal = "Toxicology Letters",

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T2 - State of the art, critical review and future needs

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AU - Tsatsakis, Aristidis M.

N1 - Funding Information: This work was supported in part by the French Agency for Food, Environmental and Occupational Health Safety (ANSES), in the framework of the Pesticide Residue Observatory action and by the Luxembourg Ministère de l’Education Supérieure et de la Recherche. The authors wish to warmly thank Laetitia Bragard for her logistic support, without which this study would not have been possible.

PY - 2012/4/25

Y1 - 2012/4/25

N2 - This paper presents the current state of the art in human hair analysis for the detection of organic pollutants associated with environmental and occupational exposure. The different chemical classes are reviewed with a special focus set on compounds that were only recently investigated. The importance of methods sensitivity and particularly the influence of this parameter on the results presented in previous publications is highlighted. This report also investigates the relevance of hair analysis as an indicator of subjects' level of exposure and underlines limitations that are still associated with this matrix. This study also presents a critical assessment of some specific aspects presented in the literature as well as future needs to strengthen the position of hair as a relevant biomarker of exposure to be used in epidemiological studies.

AB - This paper presents the current state of the art in human hair analysis for the detection of organic pollutants associated with environmental and occupational exposure. The different chemical classes are reviewed with a special focus set on compounds that were only recently investigated. The importance of methods sensitivity and particularly the influence of this parameter on the results presented in previous publications is highlighted. This report also investigates the relevance of hair analysis as an indicator of subjects' level of exposure and underlines limitations that are still associated with this matrix. This study also presents a critical assessment of some specific aspects presented in the literature as well as future needs to strengthen the position of hair as a relevant biomarker of exposure to be used in epidemiological studies.

KW - Biomarker of exposure

KW - Hair analysis

KW - Human biomonitoring

KW - Organic pollutants

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DO - 10.1016/j.toxlet.2011.10.021

M3 - Review article

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AN - SCOPUS:84859156406

SN - 0378-4274

VL - 210

SP - 119

EP - 140

JO - Toxicology Letters

JF - Toxicology Letters

IS - 2

ER -

Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs

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Keywords

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