Glutathione restricts serine metabolism to preserve regulatory T cell function

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Cell Function 100%
• Regulatory T Cell 100%
• Glutathione 100%
• Serine 100%
• Enzyme Active Site 29%
• Glutamate Cysteine Ligase Catalytic 29%
• Mouse Mutant 23%
• Enzyme 11%
• T Cell 11%
• Autoimmunity 11%
• Cysteine 11%
• Signal Transduction 5%
• Mouse Model 5%
• Genetics 5%
• Glycolysis 5%
• Glutamate-Cysteine Ligase 5%
• Mammalian Target of Rapamycin 5%
• Inflammatory Cytokine 5%
• Lipid Oxidation 5%
• Metabolic Network 5%
• Cytokine Production 5%
• Immunocompetent Cell 5%
• Cell Activation 5%
• Tumor Immunity 5%
• Immunological Tolerance 5%
• B Cell 5%
• Oxidative Phosphorylation 5%
• Downregulation 5%
• C-Terminus 5%
• Aerobic Metabolism 5%
• Lifespan 5%
• Cell Damage 5%
• Amino Acid Metabolism 5%
• Glutathione Synthase 5%
• Glutathione Synthetase 5%
• Phosphoglycerate Dehydrogenase 5%
• Alanine 5%
• Threonine 5%
• Glutamic Acid 5%

Immunology and Microbiology

• Regulatory T Cell 100%
• Cell Function 100%
• Glutathione 100%
• Serine 100%
• Cysteine 47%
• Enzyme Active Site 29%
• Dioxygen 29%
• Mouse Mutant 23%
• Autoimmunity 11%
• Immune Tolerance 5%
• Inflammatory Disorder 5%
• T Cell Activation 5%
• Inflammatory Cytokine 5%
• B Cell Activation 5%
• Cytokine Production 5%
• Mouse Model 5%
• Tumor Immunity 5%
• Immunocompetent Cell 5%
• Lifespan 5%
• T Cell 5%
• Signal Transduction 5%
• Oxidative Phosphorylation 5%
• Downregulation 5%
• Aerobic Metabolism 5%
• Carboxy Terminal Sequence 5%
• Cell Damage 5%
• Amino Acid Metabolism 5%
• Lipid Oxidation 5%
• Alanine 5%
• Threonine 5%
• In Vitro 5%
• Glycolysis 5%

Keyphrases

• Glycine Fuel 10%