TY - JOUR
T1 - Global distribution of measles genotypes and measles molecular epidemiology
AU - Rota, Paul A.
AU - Brown, Kevin
AU - Mankertz, Annette
AU - Santibanez, Sabine
AU - Shulga, Sergey
AU - Muller, Claude P.
AU - Hübschen, Judith M.
AU - Siqueira, Marilda
AU - Beirnes, Jennifer
AU - Ahmed, Hinda
AU - Triki, Henda
AU - Al-Busaidy, Suleiman
AU - Dosseh, Annick
AU - Byabamazima, Charles
AU - Smit, Sheilagh
AU - Akoua-Koffi, Chantal
AU - Bwogi, Josephine
AU - Bukenya, Henry
AU - Wairagkar, Niteen
AU - Ramamurty, Nalini
AU - Incomserb, Patcha
AU - Pattamadilok, Sirima
AU - Jee, Youngmee
AU - Lim, Wilina
AU - Xu, Wenbo
AU - Komase, Katsuhiro
AU - Takeda, Makoto
AU - Tran, Thomas
AU - Castillo-Solorzano, Carlos
AU - Chenoweth, Paul
AU - Brown, David
AU - Mulders, Mick N.
AU - Bellini, William J.
AU - Featherstone, David
N1 - Funding Information:
This study was supported in part by the World Health Organization
PY - 2011/7/1
Y1 - 2011/7/1
N2 - A critical component of laboratory surveillance for measles is the genetic characterization of circulating wild-type viruses. The World Health Organization (WHO) Measles and Rubella Laboratory Network (LabNet), provides for standardized testing in 183 countries and supports genetic characterization of currently circulating strains of measles viruses. The goal of this report is to describe the lessons learned from nearly 20 years of virologic surveillance for measles, to describe the global databases for measles sequences, and to provide regional updates about measles genotypes detected by recent surveillance activities. Virologic surveillance for measles is now well established in all of the WHO regions, and most countries have conducted at least some baseline surveillance. The WHO Global Genotype Database contains >7000 genotype reports, and the Measles Nucleotide Surveillance (MeaNS) contains >4000 entries. This sequence information has proven to be extremely useful for tracking global transmission patterns and for documenting the interruption of transmission in some countries. The future challenges will be to develop quality control programs for molecular methods and to continue to expand virologic surveillance activities in all regions.
AB - A critical component of laboratory surveillance for measles is the genetic characterization of circulating wild-type viruses. The World Health Organization (WHO) Measles and Rubella Laboratory Network (LabNet), provides for standardized testing in 183 countries and supports genetic characterization of currently circulating strains of measles viruses. The goal of this report is to describe the lessons learned from nearly 20 years of virologic surveillance for measles, to describe the global databases for measles sequences, and to provide regional updates about measles genotypes detected by recent surveillance activities. Virologic surveillance for measles is now well established in all of the WHO regions, and most countries have conducted at least some baseline surveillance. The WHO Global Genotype Database contains >7000 genotype reports, and the Measles Nucleotide Surveillance (MeaNS) contains >4000 entries. This sequence information has proven to be extremely useful for tracking global transmission patterns and for documenting the interruption of transmission in some countries. The future challenges will be to develop quality control programs for molecular methods and to continue to expand virologic surveillance activities in all regions.
UR - http://www.scopus.com/inward/record.url?scp=79960886681&partnerID=8YFLogxK
U2 - 10.1093/infdis/jir118
DO - 10.1093/infdis/jir118
M3 - Article
C2 - 21666208
AN - SCOPUS:79960886681
SN - 0022-1899
VL - 204
SP - S514-S523
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - SUPPL. 1
ER -