@article{fb8547e4bc1b4b6391f9dc968753f1ad,
title = "Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson{\textquoteleft}s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1)",
abstract = "We describe the generation of an isogenic control cell line DJ-1-delP GC13 from an induced pluripotent stem cell (iPSC) line DJ-1-delP LCSBi008-A that was derived from fibroblasts obtained from a Parkinson's disease (PD) patient. Using CRISPR/Cas9 technology, we corrected the disease causing c.471_473delGCC homozygous mutation in the PARK7 gene leading to p.158P deletion in the encoded protein DJ-1. The generated isogenic pair will be used for phenotypic analysis of PD-patient derived neurons and astrocytes.",
author = "Pauline Mencke and Zo{\'e} Hanss and Javier Jarazo and Fran{\c c}ois Massart and Arkadiusz Rybicki and Elizabet Petkovski and Enrico Glaab and Ibrahim Boussaad and Vincenzo Bonifati and {Christian Schwamborn}, Jens and Wim Mandemakers and Rejko Kr{\"u}ger",
note = "Funding Information: The current work was supported by the Fonds National de Recherche (FNR) within the PEARL Excellence Programme [FNR/P13/6682797] to RK, and the MiRisk project [C17/BM/11676395], and by the Stichting ParkinsonFonds, The Netherlands [grant SPF-1870]. Publisher Copyright: {\textcopyright} 2022 The Author(s)",
year = "2022",
month = jul,
doi = "10.1016/j.scr.2022.102815",
language = "English",
volume = "62",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
}