Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

Alanna C. Green, Petra Marttila, Nicole Kiweler, Christina Chalkiadaki, Elisée Wiita, Victoria Cookson, Antoine Lesur, Kim Eiden, François Bernardin, Karl S.A. Vallin, Sanjay Borhade, Maeve Long, Elahe Kamali Ghahe, Julio J. Jiménez-Alonso, Ann Sofie Jemth, Olga Loseva, Oliver Mortusewicz, Marianne Meyers, Elodie Viry, Annika I. JohanssonOndřej Hodek, Evert Homan, Nadilly Bonagas, Louise Ramos, Lars Sandberg, Morten Frödin, Etienne Moussay, Ana Slipicevic, Elisabeth Letellier, Jérôme Paggetti, Claus Storgaard Sørensen, Thomas Helleday*, Martin Henriksson*, Johannes Meiser*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

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Biochemistry, Genetics and Molecular Biology