TY - JOUR
T1 - Fate of β‐carotene within loaded delivery systems in food
T2 - State of knowledge
AU - Maurya, Vaibhav Kumar
AU - Shakya, Amita
AU - Aggarwal, Manjeet
AU - Gothandam, Kodiveri Muthukaliannan
AU - Bohn, Torsten
AU - Pareek, Sunil
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/3/10
Y1 - 2021/3/10
N2 - Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompati-bility and biodegradability, make these nanomaterials an attractive tool for β‐carotene delivery. Delivering β‐carotene through nanoparticles does not only improve its bioavailability/bioaccumula-tion in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory qual-ity, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoen-gineered materials now being in use, including micelles, nano/microemulsions, liposomes, nio-somes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solu-bilization, protection during processing, improved shelf‐life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β‐car-otene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β‐carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.
AB - Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompati-bility and biodegradability, make these nanomaterials an attractive tool for β‐carotene delivery. Delivering β‐carotene through nanoparticles does not only improve its bioavailability/bioaccumula-tion in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory qual-ity, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoen-gineered materials now being in use, including micelles, nano/microemulsions, liposomes, nio-somes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solu-bilization, protection during processing, improved shelf‐life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β‐car-otene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β‐carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.
KW - Beta‐carotene
KW - Bioavailability
KW - Delivery system
KW - Encapsulation
KW - Engineered nanomaterial
KW - NLCs
KW - SLNs
UR - http://www.scopus.com/inward/record.url?scp=85107082260&partnerID=8YFLogxK
U2 - 10.3390/antiox10030426
DO - 10.3390/antiox10030426
M3 - Review article
C2 - 33802152
AN - SCOPUS:85107082260
SN - 2076-3921
VL - 10
SP - 1
EP - 49
JO - Antioxidants
JF - Antioxidants
IS - 3
M1 - 426
ER -