Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk

Keyphrases

• Singleton 100%
• Common Variants 100%
• Rare Variants 60%
• Exome 40%
• Parkinson's Progression Markers Initiative 40%
• Disease Forecasting 40%
• Burden Analysis 20%
• Two-machine 20%
• Multiple Variants 20%
• Family Forms 20%
• High-risk Genes 20%
• Art Classification 20%
• Whole Exome Sequencing 20%
• Polygenic Risk Score 20%
• Rare mutation 20%
• Score-based 20%
• Disease Risk Prediction Model 20%
• Non-genetic 20%

Biochemistry, Genetics and Molecular Biology

• Genetic Risk 100%
• Rare Variant 100%
• Genetics 66%
• Exome 66%
• Amino Acids 33%
• Genetic Architecture 33%
• Exome Sequencing 33%
• Comorbidity 33%
• Polygenic Score 33%