Evidence of the influence of physical activity on the metabolic syndrome and/or on insulin resistance in pediatric populations: A systematic review

Benjamin C. Guinhouya*, Hanen Samouda, Djamel Zitouni, Christian Vilhelm, Hervé Hubert

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    50 Citations (Scopus)

    Abstract

    This study is aimed at updating the relationships between physical activity (PA) and the metabolic syndrome (MetS) and/or insulin resistance (IR) in youth. Cross-sectional, prospective cohort and intervention studies, which examined the effect of PA on MetS, its components and IR in children and adolescents (<18 yrs), were searched by applying a combination of criteria in the PubMed database. The electronic search of studies published from 20002010 yielded >150 references. Of these, 37 studies were included. Twenty-six studies (70%) were cross-sectional observation studies, and two studies (8%) were prospective cohort studies. The remaining eight studies (22%) were interventions, of which three (<10% of all included studies) were randomized controlled trials. Commonly, higher PA levels were consistently associated with an improved metabolic profile and a reduced risk for MetS and/or IR in these populations. The impact of PA on MetS and/or IR appeared to be either independent of other factors, or alternatively or simultaneously mediated by the physical fitness and adiposity of youth. However, more-robustly designed interventions (i.e., some mega-randomized controlled trials based on lifestyle interventions) and additional cohort studies are required to make definitive inference about the magnitude and role of PA as a single genuine preventive and treatment strategy for the metabolic and cardiovascular risk of youth in the current obesogenic context.

    Original languageEnglish
    Pages (from-to)361-388
    Number of pages28
    JournalInternational Journal of Pediatric Obesity
    Volume6
    Issue number5-6
    DOIs
    Publication statusPublished - Oct 2011

    Keywords

    • Childhood obesity
    • Insulin
    • Lifestyle
    • Metabolism
    • Movement behavior

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