Evaluation of commercial assay detecting specific immunoglobulin G in oral fluid for determining measles immunity in vaccinees

Jacques R. Kremer; Claude P. Muller

doi:10.1128/CDLI.12.5.668-670.2005

Evaluation of commercial assay detecting specific immunoglobulin G in oral fluid for determining measles immunity in vaccinees

Jacques R. Kremer, Claude P. Muller^*

^*Corresponding author for this work

Department of Infection and Immunity

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Abstract

A commercial assay for detection of measles immunoglobulin G (IgG) in oral fluid was evaluated in a highly vaccinated cohort using serum IgG as gold standard. In contrast to previous studies from cohorts protected by natural immunity, antibody prevalence was significantly underestimated (-7.4%; confidence interval: -1.5 to -13.2%; P = 0.01) due to a reduced sensitivity when antibody levels were low.

Original language	English
Pages (from-to)	668-670
Number of pages	3
Journal	Clinical and Diagnostic Laboratory Immunology
Volume	12
Issue number	5
DOIs	https://doi.org/10.1128/CDLI.12.5.668-670.2005
Publication status	Published - May 2005

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10.1128/CDLI.12.5.668-670.2005

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title = "Evaluation of commercial assay detecting specific immunoglobulin G in oral fluid for determining measles immunity in vaccinees",

abstract = "A commercial assay for detection of measles immunoglobulin G (IgG) in oral fluid was evaluated in a highly vaccinated cohort using serum IgG as gold standard. In contrast to previous studies from cohorts protected by natural immunity, antibody prevalence was significantly underestimated (-7.4%; confidence interval: -1.5 to -13.2%; P = 0.01) due to a reduced sensitivity when antibody levels were low.",

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Evaluation of commercial assay detecting specific immunoglobulin G in oral fluid for determining measles immunity in vaccinees

Abstract

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