TY - JOUR
T1 - Erratum
T2 - Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes b-Arrestin 2 Recruitment (Mol Pharmacol (2017) 91 (595-608) DOI: 10.1124/mol.116.107714)
AU - Dupuis, N.
AU - Laschet, C.
AU - Franssen, D.
AU - Szpakowska, M.
AU - Gilissen, J.
AU - Geubelle, P.
AU - Soni, A.
AU - Parent, A. S.
AU - Pirotte, B.
AU - Chevigné, A.
AU - Twizere, J. C.
AU - Hanson, J.
N1 - Publisher Copyright:
© 2022 American Society for Pharmacology and Experimental Therapy. All rights reserved.
PY - 2022/4/1
Y1 - 2022/4/1
N2 - In the above article [Dupuis N, Laschet C, Franssen D, Szpakowska M, Gilissen, J, Geubelle P, Soni A, Parent AS, Pirotte B, Chevigne A, Twizere JC, and Hanson J (2017) Mol Pharmacol 91:595-608 DOI: https://doi.org/10.1124/mol.116.107714], the authors recently became aware the structure of one of the active compounds, namely N-[4-(anilinocarbonyl)phenyl]-2,4-dichlorobenzamide (ChemBridge ID: 5128535, PubChem CID: 1375606, Fig. 3B), was not correct. Indeed, the active compound that was tested in the article bears a sulfonamide instead of one of the amide bonds. Thus, we have modified the original manuscript to include the correct chemical name (N-[4-(anilinosulfonyl)phenyl]-2,4-dichlorobenzamide) and structure. The EC50 and concentrations have been adapted to account for the slightly different molecular weight, which is 421 instead of 385. The structure bearing two amide bonds has been tested and had much weaker pharmacological activity. The database of the chemical supplier (Chembridge, San Diego, CA) has been also corrected. Therefore, the compound ID 5128535 can be used to acquire or refer to the correct active compound.
AB - In the above article [Dupuis N, Laschet C, Franssen D, Szpakowska M, Gilissen, J, Geubelle P, Soni A, Parent AS, Pirotte B, Chevigne A, Twizere JC, and Hanson J (2017) Mol Pharmacol 91:595-608 DOI: https://doi.org/10.1124/mol.116.107714], the authors recently became aware the structure of one of the active compounds, namely N-[4-(anilinocarbonyl)phenyl]-2,4-dichlorobenzamide (ChemBridge ID: 5128535, PubChem CID: 1375606, Fig. 3B), was not correct. Indeed, the active compound that was tested in the article bears a sulfonamide instead of one of the amide bonds. Thus, we have modified the original manuscript to include the correct chemical name (N-[4-(anilinosulfonyl)phenyl]-2,4-dichlorobenzamide) and structure. The EC50 and concentrations have been adapted to account for the slightly different molecular weight, which is 421 instead of 385. The structure bearing two amide bonds has been tested and had much weaker pharmacological activity. The database of the chemical supplier (Chembridge, San Diego, CA) has been also corrected. Therefore, the compound ID 5128535 can be used to acquire or refer to the correct active compound.
UR - http://www.scopus.com/inward/record.url?scp=85126897970&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/35321921
U2 - 10.1124/mol.116.107714err
DO - 10.1124/mol.116.107714err
M3 - Comment/debate
C2 - 35321921
AN - SCOPUS:85126897970
SN - 0026-895X
VL - 101
SP - 274
JO - Molecular Pharmacology
JF - Molecular Pharmacology
IS - 4
ER -