Effects of pre-feeding oral stimulation on oral feeding in preterm infants: A randomized clinical trial

Manon Bache*, Emmanuelle Pizon, Julien Jacobs, Michel Vaillant, Aline Lecomte

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)


Objective: To evaluate the effect of early oral stimulation before the introduction of oral feeding, over the duration of concomitant tube feeding ("transition period"), the length of hospital stay and the breastfeeding rates upon discharge in preterm infants. Study design: Preterm infants born between 26 and 33 weeks gestational age (n= 86), were randomized into an intervention and control group. Infants in the intervention group received an oral stimulation program consisting in stimulation of the oral structures for 15 min at least for 10 days, before introduction of oral feeding. Oral feeding was introduced at 34 weeks GA in both groups. Results: Breastfeeding rates upon discharge were significantly higher in the intervention than in the control group (70% versus 45.6%, p= 0.02). There was no statistical difference between the two groups in terms of the length of the transition period or the length of the hospital stay. The need for prolonged CPAP support (HR = 0.937, p= 0.030) and small size for gestational age at birth (HR = 0.338, p= 0.016) were shown to be risk factors for a prolonged transition period. Conclusion: A pre-feeding oral stimulation program improves breastfeeding rates in preterm infants. The study results suggest that oral stimulation, as used in our specific population, does not shorten the transition period to full oral feeding neither the length of hospital stay.

Original languageEnglish
Pages (from-to)125-129
Number of pages5
JournalEarly Human Development
Issue number3
Publication statusPublished - Mar 2014


  • Breastfeeding
  • Oral feeding
  • Pre-feeding oral stimulation
  • Preterm infants


Dive into the research topics of 'Effects of pre-feeding oral stimulation on oral feeding in preterm infants: A randomized clinical trial'. Together they form a unique fingerprint.

Cite this