Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study

Raul Zamora-Ros; Viktoria Knaze; Joseph A. Rothwell; Bertrand Hémon; Aurelie Moskal; Kim Overvad; Anne Tjønneland; Cecilie Kyrø; Guy Fagherazzi; Marie Christine Boutron-Ruault; Marina Touillaud; Verena Katzke; Tilman Kühn; Heiner Boeing; Jana Förster; Antonia Trichopoulou; Elissavet Valanou; Eleni Peppa; Domenico Palli; Claudia Agnoli; Fulvio Ricceri; Rosario Tumino; Maria Santucci de Magistris; Petra H.M. Peeters; H. Bas Bueno-De-Mesquita; Dagrun Engeset; Guri Skeie; Anette Hjartåker; Virginia Menéndez; Antonio Agudo; Esther Molina-Montes; José María Huerta; Aurelio Barricarte; Pilar Amiano; Emily Sonestedt; Lena Maria Nilsson; Rikard Landberg; Timothy J. Key; Kay Thee Khaw; Nicholas J. Wareham; Yunxia Lu; Nadia Slimani; Isabelle Romieu; Elio Riboli; Augustin Scalbert

doi:10.1007/s00394-015-0950-x

Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study

Raul Zamora-Ros, Viktoria Knaze, Joseph A. Rothwell, Bertrand Hémon, Aurelie Moskal, Kim Overvad, Anne Tjønneland, Cecilie Kyrø, Guy Fagherazzi, Marie Christine Boutron-Ruault, Marina Touillaud, Verena Katzke, Tilman Kühn, Heiner Boeing, Jana Förster, Antonia Trichopoulou, Elissavet Valanou, Eleni Peppa, Domenico Palli, Claudia AgnoliFulvio Ricceri, Rosario Tumino, Maria Santucci de Magistris, Petra H.M. Peeters, H. Bas Bueno-De-Mesquita, Dagrun Engeset, Guri Skeie, Anette Hjartåker, Virginia Menéndez, Antonio Agudo, Esther Molina-Montes, José María Huerta, Aurelio Barricarte, Pilar Amiano, Emily Sonestedt, Lena Maria Nilsson, Rikard Landberg, Timothy J. Key, Kay Thee Khaw, Nicholas J. Wareham, Yunxia Lu, Nadia Slimani, Isabelle Romieu, Elio Riboli, Augustin Scalbert^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

339 Citations (Scopus)

Abstract

Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.

Original language	English
Pages (from-to)	1359-1375
Number of pages	17
Journal	European Journal of Nutrition
Volume	55
Issue number	4
DOIs	https://doi.org/10.1007/s00394-015-0950-x
Publication status	Published - 17 Jun 2016
Externally published	Yes

Keywords

Dietary intake
EPIC
Food sources
Polyphenols

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10.1007/s00394-015-0950-x

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Zamora-Ros, R., Knaze, V., Rothwell, J. A., Hémon, B., Moskal, A., Overvad, K., Tjønneland, A., Kyrø, C., Fagherazzi, G., Boutron-Ruault, M. C., Touillaud, M., Katzke, V., Kühn, T., Boeing, H., Förster, J., Trichopoulou, A., Valanou, E., Peppa, E., Palli, D., ... Scalbert, A. (2016). Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study. European Journal of Nutrition, 55(4), 1359-1375. https://doi.org/10.1007/s00394-015-0950-x

@article{4c50cf3a8310430da8c56989e16b05bd,

title = "Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study",

abstract = "Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.",

keywords = "Dietary intake, EPIC, Food sources, Polyphenols",

author = "Raul Zamora-Ros and Viktoria Knaze and Rothwell, {Joseph A.} and Bertrand H{\'e}mon and Aurelie Moskal and Kim Overvad and Anne Tj{\o}nneland and Cecilie Kyr{\o} and Guy Fagherazzi and Boutron-Ruault, {Marie Christine} and Marina Touillaud and Verena Katzke and Tilman K{\"u}hn and Heiner Boeing and Jana F{\"o}rster and Antonia Trichopoulou and Elissavet Valanou and Eleni Peppa and Domenico Palli and Claudia Agnoli and Fulvio Ricceri and Rosario Tumino and {de Magistris}, {Maria Santucci} and Peeters, {Petra H.M.} and {Bas Bueno-De-Mesquita}, H. and Dagrun Engeset and Guri Skeie and Anette Hjart{\aa}ker and Virginia Men{\'e}ndez and Antonio Agudo and Esther Molina-Montes and Huerta, {Jos{\'e} Mar{\'i}a} and Aurelio Barricarte and Pilar Amiano and Emily Sonestedt and Nilsson, {Lena Maria} and Rikard Landberg and Key, {Timothy J.} and Khaw, {Kay Thee} and Wareham, {Nicholas J.} and Yunxia Lu and Nadia Slimani and Isabelle Romieu and Elio Riboli and Augustin Scalbert",

note = "Publisher Copyright: {\textcopyright} Springer-Verlag Berlin Heidelberg 2015.",

year = "2016",

month = jun,

day = "17",

doi = "10.1007/s00394-015-0950-x",

language = "English",

volume = "55",

pages = "1359--1375",

journal = "European Journal of Nutrition",

issn = "1436-6207",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "4",

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Zamora-Ros, R, Knaze, V, Rothwell, JA, Hémon, B, Moskal, A, Overvad, K, Tjønneland, A, Kyrø, C, Fagherazzi, G, Boutron-Ruault, MC, Touillaud, M, Katzke, V, Kühn, T, Boeing, H, Förster, J, Trichopoulou, A, Valanou, E, Peppa, E, Palli, D, Agnoli, C, Ricceri, F, Tumino, R, de Magistris, MS, Peeters, PHM, Bas Bueno-De-Mesquita, H, Engeset, D, Skeie, G, Hjartåker, A, Menéndez, V, Agudo, A, Molina-Montes, E, Huerta, JM, Barricarte, A, Amiano, P, Sonestedt, E, Nilsson, LM, Landberg, R, Key, TJ, Khaw, KT, Wareham, NJ, Lu, Y, Slimani, N, Romieu, I, Riboli, E & Scalbert, A 2016, 'Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study', European Journal of Nutrition, vol. 55, no. 4, pp. 1359-1375. https://doi.org/10.1007/s00394-015-0950-x

TY - JOUR

T1 - Dietary polyphenol intake in europe

T2 - The european prospective investigation into cancer and nutrition (EPIC) study

AU - Zamora-Ros, Raul

AU - Knaze, Viktoria

AU - Rothwell, Joseph A.

AU - Hémon, Bertrand

AU - Moskal, Aurelie

AU - Overvad, Kim

AU - Tjønneland, Anne

AU - Kyrø, Cecilie

AU - Fagherazzi, Guy

AU - Boutron-Ruault, Marie Christine

AU - Touillaud, Marina

AU - Katzke, Verena

AU - Kühn, Tilman

AU - Boeing, Heiner

AU - Förster, Jana

AU - Trichopoulou, Antonia

AU - Valanou, Elissavet

AU - Peppa, Eleni

AU - Palli, Domenico

AU - Agnoli, Claudia

AU - Ricceri, Fulvio

AU - Tumino, Rosario

AU - de Magistris, Maria Santucci

AU - Peeters, Petra H.M.

AU - Bas Bueno-De-Mesquita, H.

AU - Engeset, Dagrun

AU - Skeie, Guri

AU - Hjartåker, Anette

AU - Menéndez, Virginia

AU - Agudo, Antonio

AU - Molina-Montes, Esther

AU - Huerta, José María

AU - Barricarte, Aurelio

AU - Amiano, Pilar

AU - Sonestedt, Emily

AU - Nilsson, Lena Maria

AU - Landberg, Rikard

AU - Key, Timothy J.

AU - Khaw, Kay Thee

AU - Wareham, Nicholas J.

AU - Lu, Yunxia

AU - Slimani, Nadia

AU - Romieu, Isabelle

AU - Riboli, Elio

AU - Scalbert, Augustin

PY - 2016/6/17

Y1 - 2016/6/17

N2 - Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.

AB - Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.

KW - Dietary intake

KW - EPIC

KW - Food sources

KW - Polyphenols

UR - http://www.scopus.com/inward/record.url?scp=84931036081&partnerID=8YFLogxK

U2 - 10.1007/s00394-015-0950-x

DO - 10.1007/s00394-015-0950-x

M3 - Article

C2 - 26081647

AN - SCOPUS:84931036081

SN - 1436-6207

VL - 55

SP - 1359

EP - 1375

JO - European Journal of Nutrition

JF - European Journal of Nutrition

IS - 4

ER -

Dietary polyphenol intake in europe: The european prospective investigation into cancer and nutrition (EPIC) study

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