TY - JOUR
T1 - Dietary polyphenol intake in europe
T2 - The european prospective investigation into cancer and nutrition (EPIC) study
AU - Zamora-Ros, Raul
AU - Knaze, Viktoria
AU - Rothwell, Joseph A.
AU - Hémon, Bertrand
AU - Moskal, Aurelie
AU - Overvad, Kim
AU - Tjønneland, Anne
AU - Kyrø, Cecilie
AU - Fagherazzi, Guy
AU - Boutron-Ruault, Marie Christine
AU - Touillaud, Marina
AU - Katzke, Verena
AU - Kühn, Tilman
AU - Boeing, Heiner
AU - Förster, Jana
AU - Trichopoulou, Antonia
AU - Valanou, Elissavet
AU - Peppa, Eleni
AU - Palli, Domenico
AU - Agnoli, Claudia
AU - Ricceri, Fulvio
AU - Tumino, Rosario
AU - de Magistris, Maria Santucci
AU - Peeters, Petra H.M.
AU - Bas Bueno-De-Mesquita, H.
AU - Engeset, Dagrun
AU - Skeie, Guri
AU - Hjartåker, Anette
AU - Menéndez, Virginia
AU - Agudo, Antonio
AU - Molina-Montes, Esther
AU - Huerta, José María
AU - Barricarte, Aurelio
AU - Amiano, Pilar
AU - Sonestedt, Emily
AU - Nilsson, Lena Maria
AU - Landberg, Rikard
AU - Key, Timothy J.
AU - Khaw, Kay Thee
AU - Wareham, Nicholas J.
AU - Lu, Yunxia
AU - Slimani, Nadia
AU - Romieu, Isabelle
AU - Riboli, Elio
AU - Scalbert, Augustin
N1 - Funding Information:
This study was supported by the Institut National du Cancer, Paris (INCa Grants 2011-105), and the Wereld Kanker Onderzoek Fonds (WCRF NL 2012/604). The EPIC study was supported by the European Commission: Public Health and Consumer Protection Directorate 1993â2004, Research Directorate-General 2005; the French National Cancer Institute (LâInstitut National du Cancer; INCA) (Grant Number 2009-139); Ligue contre le Cancer; the Institut Gustave Roussy; the Mutuelle Générale de lâEducation Nationale; the Institut National de la Santé et de la Recherche Médicale (INSERM); the German Cancer Aid; the German Cancer Research Center (DKFZ); the German Federal Ministry of Education and Research; the Danish Cancer Society; The Danish Council for Strategic Research; Health Research Fund (FIS) of the Spanish Ministry of Health (RTICC (DR06/0020/0091); the participating regional governments from Asturias, AndalucÃa, Murcia, Navarra and Vasco Country and the Catalan Institute of Oncology of Spain; Cancer Research UK; Medical Research Council, UK; the Stroke Association, UK; British Heart Foundation; Department of Health, UK; Food Standards Agency, UK; the Wellcome Trust, UK; the Hellenic Health Foundation (Greece); Italian Association for Research on Cancer; Compagnia San Paolo, Italy; Dutch Ministry of Public Health, Welfare and Sports; Dutch Ministry of Health; Dutch Prevention Funds; LK Research Funds; Dutch ZON (Zorg Onderzoek Nederland); World Cancer Research Fund (WCRF); Statistics Netherlands (the Netherlands); Swedish Cancer Society; Swedish Scientific Council; Regional Government of Skane, The County Council of Västerbotten, Sweden; NordforskâCentre of Excellence programme; some authors are partners of ECNIS, a network of excellence of the 6th Framework Program of the European Commission.
Funding Information:
This study was supported by the Institut National du Cancer, Paris (INCa Grants 2011-105), and the Wereld Kanker Onderzoek Fonds (WCRF NL 2012/604). The EPIC study was supported by the European Commission: Public Health and Consumer Protection Directorate 1993–2004, Research Directorate-General 2005; the French National Cancer Institute (L’Institut National du Cancer; INCA) (Grant Number 2009-139); Ligue contre le Cancer; the Institut Gustave Roussy; the Mutuelle Générale de l’Education Nationale; the Institut National de la Santé et de la Recherche Médicale (INSERM); the German Cancer Aid; the German Cancer Research Center (DKFZ); the German Federal Ministry of Education and Research; the Danish Cancer Society; The Danish Council for Strategic Research; Health Research Fund (FIS) of the Spanish Ministry of Health (RTICC (DR06/0020/0091); the participating regional governments from Asturias, Andalucía, Murcia, Navarra and Vasco Country and the Catalan Institute of Oncology of Spain; Cancer Research UK; Medical Research Council, UK; the Stroke Association, UK; British Heart Foundation; Department of Health, UK; Food Standards Agency, UK; the Wellcome Trust, UK; the Hellenic Health Foundation (Greece); Italian Association for Research on Cancer; Compagnia San Paolo, Italy; Dutch Ministry of Public Health, Welfare and Sports; Dutch Ministry of Health; Dutch Prevention Funds; LK Research Funds; Dutch ZON (Zorg Onderzoek Nederland); World Cancer Research Fund (WCRF); Statistics Netherlands (the Netherlands); Swedish Cancer Society; Swedish Scientific Council; Regional Government of Skane, The County Council of Västerbotten, Sweden; Nordforsk—Centre of Excellence programme; some authors are partners of ECNIS, a network of excellence of the 6th Framework Program of the European Commission.
Publisher Copyright:
© Springer-Verlag Berlin Heidelberg 2015.
PY - 2016/6/17
Y1 - 2016/6/17
N2 - Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.
AB - Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. To date, limited data exist on intake of polyphenols in populations. The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. Methods Dietary data at baseline were collected using a standardized 24-h dietary recall software administered to 36,037 adult subjects. Dietary data were linked with Phenol- Explorer, a database with data on 502 individual polyphenols in 452 foods and data on polyphenol losses due to cooking and food processing. Results Mean total polyphenol intake was the highest in Aarhus—Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. The main polyphenol contributors were phenolic acids (52.5–56.9 %), except in men from MED countries and in the UK health-conscious group where they were flavonoids (49.1–61.7 %). Coffee, tea, and fruits were the most important food sources of total polyphenols. A total of 437 different individual polyphenols were consumed, including 94 consumed at a level [1 mg/day. The most abundant ones were the caffeoylquinic acids and the proanthocyanidin oligomers and polymers. Conclusion This study describes the large number of dietary individual polyphenols consumed and the high variability of their intakes between European populations, particularly between MED and non-MED countries.
KW - Dietary intake
KW - EPIC
KW - Food sources
KW - Polyphenols
UR - http://www.scopus.com/inward/record.url?scp=84931036081&partnerID=8YFLogxK
U2 - 10.1007/s00394-015-0950-x
DO - 10.1007/s00394-015-0950-x
M3 - Article
C2 - 26081647
AN - SCOPUS:84931036081
SN - 1436-6207
VL - 55
SP - 1359
EP - 1375
JO - European Journal of Nutrition
JF - European Journal of Nutrition
IS - 4
ER -