TY - JOUR
T1 - Developing a medication adherence technologies repository
T2 - Proposed structure and protocol for an online real-time Delphi study
AU - Nabergoj Makovec, Urska
AU - Goetzinger, Catherine
AU - Ribaut, Janette
AU - Barnestein-Fonseca, Pilar
AU - Haupenthal, Frederik
AU - Herdeiro, Maria Teresa
AU - Grant, Sean Patrick
AU - Jácome, Cristina
AU - Roque, Fatima
AU - Smits, Dins
AU - Tadic, Ivana
AU - Dima, Alexandra L.
AU - European Network to Advance Best practices and technoLogy on medication adherencE (ENABLE)
AU - European Network to Advance Best practices and technoLogy on medication adherencE (ENABLE)
N1 - Funding This work was supported by COST Action ENABLE—European Network to Advance Best practices & technoLogy on medication adherencE’, number CA19132. CG was supported by a PhD grant financed by the Action LIONS Vaincre le Cancer. The work of IT was partially supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (project no.451-03-68/2022-14/200161). AD was supported by an IDEXLYON grant (16-IDEX-0005; 2018-2021) during the preparation of this manuscript.
Publisher Copyright:
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2022/4/22
Y1 - 2022/4/22
N2 - Introduction An online interactive repository of available medication adherence technologies may facilitate their selection and adoption by different stakeholders. Developing a repository is among the main objectives of the European Network to Advance Best practices and technoLogy on medication adherencE (ENABLE) COST Action (CA19132). However, meeting the needs of diverse stakeholders requires careful consideration of the repository structure. Methods and analysis A real-time online Delphi study by stakeholders from 39 countries with research, practice, policy, patient representation and technology development backgrounds will be conducted. Eleven ENABLE members from 9 European countries formed an interdisciplinary steering committee to develop the repository structure, prepare study protocol and perform it. Definitions of medication adherence technologies and their attributes were developed iteratively through literature review, discussions within the steering committee and ENABLE Action members, following ontology development recommendations. Three domains (product and provider information (D1), medication adherence descriptors (D2) and evaluation and implementation (D3)) branching in 13 attribute groups are proposed: product and provider information, target use scenarios, target health conditions, medication regimen, medication adherence management components, monitoring/measurement methods and targets, intervention modes of delivery, target behaviour determinants, behaviour change techniques, intervention providers, intervention settings, quality indicators and implementation indicators. Stakeholders will evaluate the proposed definition and attributes' relevance, clarity and completeness and have multiple opportunities to reconsider their evaluations based on aggregated feedback in real-time. Data collection will stop when the predetermined response rate will be achieved. We will quantify agreement and perform analyses of process indicators on the whole sample and per stakeholder group. Ethics and dissemination Ethical approval for the COST ENABLE activities was granted by the Malaga Regional Research Ethics Committee. The Delphi protocol was considered compliant regarding data protection and security by the Data Protection Officer from University of Basel. Findings from the Delphi study will form the basis for the ENABLE repository structure and related activities.
AB - Introduction An online interactive repository of available medication adherence technologies may facilitate their selection and adoption by different stakeholders. Developing a repository is among the main objectives of the European Network to Advance Best practices and technoLogy on medication adherencE (ENABLE) COST Action (CA19132). However, meeting the needs of diverse stakeholders requires careful consideration of the repository structure. Methods and analysis A real-time online Delphi study by stakeholders from 39 countries with research, practice, policy, patient representation and technology development backgrounds will be conducted. Eleven ENABLE members from 9 European countries formed an interdisciplinary steering committee to develop the repository structure, prepare study protocol and perform it. Definitions of medication adherence technologies and their attributes were developed iteratively through literature review, discussions within the steering committee and ENABLE Action members, following ontology development recommendations. Three domains (product and provider information (D1), medication adherence descriptors (D2) and evaluation and implementation (D3)) branching in 13 attribute groups are proposed: product and provider information, target use scenarios, target health conditions, medication regimen, medication adherence management components, monitoring/measurement methods and targets, intervention modes of delivery, target behaviour determinants, behaviour change techniques, intervention providers, intervention settings, quality indicators and implementation indicators. Stakeholders will evaluate the proposed definition and attributes' relevance, clarity and completeness and have multiple opportunities to reconsider their evaluations based on aggregated feedback in real-time. Data collection will stop when the predetermined response rate will be achieved. We will quantify agreement and perform analyses of process indicators on the whole sample and per stakeholder group. Ethics and dissemination Ethical approval for the COST ENABLE activities was granted by the Malaga Regional Research Ethics Committee. The Delphi protocol was considered compliant regarding data protection and security by the Data Protection Officer from University of Basel. Findings from the Delphi study will form the basis for the ENABLE repository structure and related activities.
KW - health informatics
KW - public health
KW - social medicine
UR - http://www.scopus.com/inward/record.url?scp=85128802668&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/35459677
U2 - 10.1136/bmjopen-2021-059674
DO - 10.1136/bmjopen-2021-059674
M3 - Article
C2 - 35459677
AN - SCOPUS:85128802668
SN - 2044-6055
VL - 12
JO - BMJ Open
JF - BMJ Open
IS - 4
M1 - e059674
ER -