Detection and Discovery of Coronaviruses in Wild Bird Populations

Chantal J. Snoeck*, Siamak Zohari

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)

Abstract

Wild birds are natural hosts of multiple microbial agents, including a wide diversity of coronaviruses. Here we describe a pan-Coronavirus detection RT-PCR method to identify those viruses regardless of the coronavirus genus or nature of the specimen. We also describe a protocol using high-throughput sequencing technologies to obtain their entire genome, which overcomes the inherent difficulties of wild bird coronavirus sequencing, that is, their genetic diversity and the lack of virus isolation methods.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages41-53
Number of pages13
DOIs
Publication statusPublished - 2020

Publication series

NameMethods in Molecular Biology
Volume2203
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Deltacoronavirus
  • Gammacoronavirus
  • Illumina MiSeq
  • Next-generation sequencing
  • Pan-Coronavirus
  • RT-PCR
  • Sample collection
  • Wild birds

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