@article{3809ef9bb90e424389f5458d4a956e75,
title = "Cytotoxic triterpenoids from Abies recurvata",
abstract = "Nine triterpenoids (neoabiestrines A-I, 1-9) including six rearranged lanostanes (1-6) and a rare cycloart-7-ene (7) were isolated from Abies recurvata together with ten known compounds. Their structures were determined by detailed analysis of NMR and MS spectroscopic data. The absolute configurations of 1 and 8 were determined by Cu-Ka X-ray crystallography. Compound 6 showed potent anti-proliferative effect against THP-1 tumor cells with an IC 50 value of 17.8 μg/mL.",
keywords = "Abies recurvata, Cu-Ka X-ray crystallography, Cytotoxicity, Pinaceae, Triterpenoids",
author = "Li, \{Yong Li\} and Gao, \{Yan Xia\} and Yang, \{Xian Wen\} and Jin, \{Hui Zi\} and Ji Ye and Luke Simmons and Ning Wang and Andre Steinmetz and Zhang, \{Wei Dong\}",
note = "Funding Information: This work was supported by the Special Program for New Drug Innovation of the Ministry of Science and Technology, China ( 2009ZX09308-005 ), the National Natural Science Foundation of China ( 41176148 , 21002110 , and 30725045 ), the Shanghai Leading Academic Discipline Project ( B906 ), and in part by the FP7 People Work Program ( FP7-People-IRSES-2008, No. 230232 ). ",
year = "2012",
month = sep,
doi = "10.1016/j.phytochem.2012.05.032",
language = "English",
volume = "81",
pages = "159--164",
journal = "Phytochemistry",
issn = "0031-9422",
publisher = "Elsevier Ltd.",
}