COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight

Charles Auffray*, Rudi Balling, Niklas Blomberg, Myrna C. Bonaldo, Bertrand Boutron, Samir Brahmachari, Christian Bréchot, Alfredo Cesario, Sai Juan Chen, Karine Clément, Daria Danilenko, Alberto Di Meglio, Andrea Gelemanović, Carole Goble, Takashi Gojobori, Jason D. Goldman, Michel Goldman, Yi Ke Guo, James Heath, Leroy HoodPeter Hunter, Li Jin, Hiroaki Kitano, Bartha Knoppers, Doron Lancet, Catherine Larue, Mark Lathrop, Martine Laville, Ariel B. Lindner, Antoine Magnan, Andres Metspalu, Edgar Morin, Lisa F.P. Ng, Laurent Nicod, Denis Noble, Laurent Nottale, Helga Nowotny, Theresa Ochoa, Iruka N. Okeke, Tolu Oni, Peter Openshaw, Mehmet Oztürk, Susanna Palkonen, Janusz T. Paweska, Christophe Pison, Mihael H. Polymeropoulos, Christian Pristipino, Ulrike Protzer, Josep Roca, Damjana Rozman

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


Background: Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. Vision: The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21st century. Mission: For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies.

Original languageEnglish
Pages (from-to)1-18
Number of pages18
Publication statusPublished - 2021


  • Coalition
  • Coronavirus
  • COVID-19
  • Pandemic
  • SARS-CoV-2
  • Solidarity
  • Systemic crisis
  • Systemic response


Dive into the research topics of 'COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight'. Together they form a unique fingerprint.

Cite this