TY - JOUR
T1 - Contributory Factors to Caregiver Burden in Parkinson Disease
AU - Grün, Daniel
AU - Pieri, Vannina
AU - Vaillant, Michel
AU - Diederich, Nico J.
N1 - Publisher Copyright:
© 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Background In Parkinson disease (PD), patients often require burdensome assistance, delivered by informal caregivers (eg, spouse). Design Prospective questionnaire and clinical-based investigation. Objectives To investigate both patient- and caregiver-derived factors contributing to caregiver burden (CB). Methods We assessed, in 59 patient-caregiver pairs, various motor, nonmotor, and cognitive symptoms as well as quality of life by standardized tests and questionnaires. Repercussions on the caregiver were evaluated by Zarit Burden Interview, Health-related Quality of Life (HrQoL), Generalized Anxiety Disorder Assessment-7, Patient Health Questionnaire-9, and the Montreal Cognitive Assessment. Transcultural comparison was ensured by validation of the tests in the 3 used languages. Results Sleep problems and autonomic dysfunction of the patient strongly impact CB (r = −0.414 to −0.335, P < .01) and HrQoL of the caregiver (r = −0.335 to −0.314, P < .05). Higher CB is less strongly linked with patient's motor impairment (P < .05). Large time investment, including nocturnal care in 41% of the caregivers, strongly influences CB (P < .001). The mood, but not the cognitive status, of the caregiver is directly linked to CB and HrQoL of the caregiver (P < .01). Conclusion In PD, the CB is primarily dependent on patients' nonmotor symptoms. Patient care requires considerable time investment and can trigger depression in the caregiver.
AB - Background In Parkinson disease (PD), patients often require burdensome assistance, delivered by informal caregivers (eg, spouse). Design Prospective questionnaire and clinical-based investigation. Objectives To investigate both patient- and caregiver-derived factors contributing to caregiver burden (CB). Methods We assessed, in 59 patient-caregiver pairs, various motor, nonmotor, and cognitive symptoms as well as quality of life by standardized tests and questionnaires. Repercussions on the caregiver were evaluated by Zarit Burden Interview, Health-related Quality of Life (HrQoL), Generalized Anxiety Disorder Assessment-7, Patient Health Questionnaire-9, and the Montreal Cognitive Assessment. Transcultural comparison was ensured by validation of the tests in the 3 used languages. Results Sleep problems and autonomic dysfunction of the patient strongly impact CB (r = −0.414 to −0.335, P < .01) and HrQoL of the caregiver (r = −0.335 to −0.314, P < .05). Higher CB is less strongly linked with patient's motor impairment (P < .05). Large time investment, including nocturnal care in 41% of the caregivers, strongly influences CB (P < .001). The mood, but not the cognitive status, of the caregiver is directly linked to CB and HrQoL of the caregiver (P < .01). Conclusion In PD, the CB is primarily dependent on patients' nonmotor symptoms. Patient care requires considerable time investment and can trigger depression in the caregiver.
KW - Parkinson disease
KW - caregiver burden
KW - motor symptoms
KW - nonmotor symptoms
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=84975678141&partnerID=8YFLogxK
U2 - 10.1016/j.jamda.2016.03.004
DO - 10.1016/j.jamda.2016.03.004
M3 - Article
C2 - 27143237
AN - SCOPUS:84975678141
SN - 1525-8610
VL - 17
SP - 626
EP - 632
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
IS - 7
ER -