TY - JOUR
T1 - Contributory Factors to Caregiver Burden in Parkinson Disease
AU - Grün, Daniel
AU - Pieri, Vannina
AU - Vaillant, Michel
AU - Diederich, Nico J.
N1 - Funding Information:
The study was partially funded by the Foundation Think, Luxembourg. NJD is investigator in HELP-PD, and has been supported by the Fonds National de Recherche, Luxembourg.
Funding Information:
We are grateful for supporting the recruitment to Drs B.Wauschkuhn, S. Thoma, J. Thoma, and R. Metz and to the Luxembourgish Parkinson Association and for partial financial funding to the Foundation Think, Luxembourg.
Publisher Copyright:
© 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Background In Parkinson disease (PD), patients often require burdensome assistance, delivered by informal caregivers (eg, spouse). Design Prospective questionnaire and clinical-based investigation. Objectives To investigate both patient- and caregiver-derived factors contributing to caregiver burden (CB). Methods We assessed, in 59 patient-caregiver pairs, various motor, nonmotor, and cognitive symptoms as well as quality of life by standardized tests and questionnaires. Repercussions on the caregiver were evaluated by Zarit Burden Interview, Health-related Quality of Life (HrQoL), Generalized Anxiety Disorder Assessment-7, Patient Health Questionnaire-9, and the Montreal Cognitive Assessment. Transcultural comparison was ensured by validation of the tests in the 3 used languages. Results Sleep problems and autonomic dysfunction of the patient strongly impact CB (r = −0.414 to −0.335, P < .01) and HrQoL of the caregiver (r = −0.335 to −0.314, P < .05). Higher CB is less strongly linked with patient's motor impairment (P < .05). Large time investment, including nocturnal care in 41% of the caregivers, strongly influences CB (P < .001). The mood, but not the cognitive status, of the caregiver is directly linked to CB and HrQoL of the caregiver (P < .01). Conclusion In PD, the CB is primarily dependent on patients' nonmotor symptoms. Patient care requires considerable time investment and can trigger depression in the caregiver.
AB - Background In Parkinson disease (PD), patients often require burdensome assistance, delivered by informal caregivers (eg, spouse). Design Prospective questionnaire and clinical-based investigation. Objectives To investigate both patient- and caregiver-derived factors contributing to caregiver burden (CB). Methods We assessed, in 59 patient-caregiver pairs, various motor, nonmotor, and cognitive symptoms as well as quality of life by standardized tests and questionnaires. Repercussions on the caregiver were evaluated by Zarit Burden Interview, Health-related Quality of Life (HrQoL), Generalized Anxiety Disorder Assessment-7, Patient Health Questionnaire-9, and the Montreal Cognitive Assessment. Transcultural comparison was ensured by validation of the tests in the 3 used languages. Results Sleep problems and autonomic dysfunction of the patient strongly impact CB (r = −0.414 to −0.335, P < .01) and HrQoL of the caregiver (r = −0.335 to −0.314, P < .05). Higher CB is less strongly linked with patient's motor impairment (P < .05). Large time investment, including nocturnal care in 41% of the caregivers, strongly influences CB (P < .001). The mood, but not the cognitive status, of the caregiver is directly linked to CB and HrQoL of the caregiver (P < .01). Conclusion In PD, the CB is primarily dependent on patients' nonmotor symptoms. Patient care requires considerable time investment and can trigger depression in the caregiver.
KW - Parkinson disease
KW - caregiver burden
KW - motor symptoms
KW - nonmotor symptoms
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=84975678141&partnerID=8YFLogxK
U2 - 10.1016/j.jamda.2016.03.004
DO - 10.1016/j.jamda.2016.03.004
M3 - Article
C2 - 27143237
AN - SCOPUS:84975678141
SN - 1525-8610
VL - 17
SP - 626
EP - 632
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
IS - 7
ER -