Chemopreventive and therapeutic effects of curcumin

Annelyse Duvoix; Romain Blasius; Sylvie Delhalle; Michaël Schnekenburger; Franck Morceau; Estelle Henry; Mario Dicato; Marc Diederich

doi:10.1016/j.canlet.2004.09.041

Chemopreventive and therapeutic effects of curcumin

Annelyse Duvoix, Romain Blasius, Sylvie Delhalle, Michaël Schnekenburger, Franck Morceau, Estelle Henry, Mario Dicato, Marc Diederich^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

795 Citations (Scopus)

Abstract

Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.

Original language	English
Pages (from-to)	181-190
Number of pages	10
Journal	Cancer Letters
Volume	223
Issue number	2
DOIs	https://doi.org/10.1016/j.canlet.2004.09.041
Publication status	Published - 8 Jun 2005
Externally published	Yes

Keywords

Apoptosis
Cancer
Chemopreventive agent
Curcumin
Drug metabolism

Access to Document

10.1016/j.canlet.2004.09.041

Cite this

@article{c0520a868bb843e29b6d08bb862b8600,

title = "Chemopreventive and therapeutic effects of curcumin",

abstract = "Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.",

keywords = "Apoptosis, Cancer, Chemopreventive agent, Curcumin, Drug metabolism",

author = "Annelyse Duvoix and Romain Blasius and Sylvie Delhalle and Micha{\"e}l Schnekenburger and Franck Morceau and Estelle Henry and Mario Dicato and Marc Diederich",

year = "2005",

month = jun,

day = "8",

doi = "10.1016/j.canlet.2004.09.041",

language = "English",

volume = "223",

pages = "181--190",

journal = "Cancer Letters",

issn = "0304-3835",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Chemopreventive and therapeutic effects of curcumin

AU - Duvoix, Annelyse

AU - Blasius, Romain

AU - Delhalle, Sylvie

AU - Schnekenburger, Michaël

AU - Morceau, Franck

AU - Henry, Estelle

AU - Dicato, Mario

AU - Diederich, Marc

PY - 2005/6/8

Y1 - 2005/6/8

N2 - Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.

AB - Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.

KW - Apoptosis

KW - Cancer

KW - Chemopreventive agent

KW - Curcumin

KW - Drug metabolism

UR - http://www.scopus.com/inward/record.url?scp=19344368071&partnerID=8YFLogxK

U2 - 10.1016/j.canlet.2004.09.041

DO - 10.1016/j.canlet.2004.09.041

M3 - Review article

C2 - 15896452

AN - SCOPUS:19344368071

SN - 0304-3835

VL - 223

SP - 181

EP - 190

JO - Cancer Letters

JF - Cancer Letters

IS - 2

ER -

Chemopreventive and therapeutic effects of curcumin

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this