Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model

Keyphrases

• Mathematical Model 100%
• Tumor Cells 100%
• Cell Adhesion 100%
• Adhesion Receptors 100%
• Tumor Dissemination 100%
• Adhesion 80%
• Cell Population 60%
• Epithelial-mesenchymal Transition 60%
• Epithelial Cells 40%
• Cell Density 40%
• Extrinsic Cues 40%
• Local Environment 40%
• Cell Dissemination 40%
• Local Cells 40%
• Receptor Regulation 40%
• Tumor Mass 20%
• Genetic Variability 20%
• Primary Tumor 20%
• Adhesion Molecules 20%
• Cancer Invasion 20%
• Mesenchymal Phenotype 20%
• Loss of Control 20%
• E-cadherin 20%
• Epithelial Phenotype 20%
• Spatial Heterogeneity 20%
• Extrinsic Factors 20%
• Intratumor 20%
• Cancer Metastasis 20%
• Neighboring Cells 20%
• Additional Control 20%
• Intrinsic Factors 20%
• Healthy Cells 20%
• Cancer Cell Dissemination 20%
• Cellular Automata 20%
• Universal Triggers 20%
• Early Dissemination 20%
• Epigenetic Variability 20%
• Partially Compensated 20%
• Tumor Adhesion 20%

Medicine and Dentistry

• Tumor Cell 100%
• Cell Adhesion 100%
• Adhesion Receptor 62%
• Cell Population 37%
• Mesenchymal-Epithelial Transition 37%
• Epithelial Cell 25%
• Cell Density 25%
• Cancer Cell 12%
• Cell Invasion 12%
• Primary Tumor 12%
• Intrinsic Factor 12%
• Uvomorulin 12%
• Tumor 12%
• Cyanocobalamin 12%
• Adhesive Agent 12%
• Cell Adhesion Proteins 12%
• Genetics 12%

Biochemistry, Genetics and Molecular Biology

• Cell Adhesion 100%
• Mesenchymal-Epithelial Transition 100%
• Cell Density 66%
• Genetics 33%
• Cancer Cell 33%
• Cell Invasion 33%
• Cyanocobalamin 33%
• Cell Adhesion Proteins 33%
• Intrinsic Factor 33%
• Cadherin 33%