Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices

Periklis Charalampous, Vanessa Gorasso, Dietrich Plass, Sara M Pires, Elena von der Lippe, Alibek Mereke, Jane Idavain, Katarzyna Kissimova-Skarbek, Joana Nazaré Morgado, Che Henry Ngwa, Isabel Noguer, Alicia Padron-Monedero, María José Santi-Cano, Rodrigo Sarmiento, Brecht Devleesschauwer, Juanita A Haagsma, COST Action CA18218 participants, Hanène Samouda

Research output: Contribution to journalArticleResearchpeer-review

Abstract

BACKGROUND: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to: (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD DALYs.

METHODS: NCD BoD studies were systematically searched in international electronic literature databases and in grey literature. We included all BoD studies that used the DALY metric to quantify the health impact of one or more NCDs in countries belonging to the European Region.

RESULTS: A total of 163 BoD studies were retained: 96 (59%) were single-country or sub-national studies and 67 (41%) considered more than one country. Of the single-country studies, 29 (30%) consisted of secondary analyses using existing Global Burden of Disease (GBD) results. Mortality data were mainly derived (49%) from vital statistics. Morbidity data were frequently (40%) drawn from routine administrative and survey datasets, including disease registries and hospital discharge databases. The majority (60%) of national BoD studies reported mortality corrections. Multimorbidity adjustments were performed in 18% of national BoD studies.

CONCLUSION: The number of national NCD BoD assessments across Europe increased over time, driven by an increase in BoD studies that consisted of secondary data analysis of GBD study findings. Ambiguity in reporting of the use of NCD-specific BoD methods underline the need for reporting guidelines of BoD studies to enhance transparency of NCD BoD estimates across Europe.

Original languageEnglish
Pages (from-to)289-296
Number of pages8
JournalEuropean Journal of Public Health
Volume32
Issue number2
Early online date7 Jan 2022
DOIs
Publication statusPublished - 1 Apr 2022

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