Abstract
Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to sensitive responsive photoluminescent probes for protein kinase CK2 that emitted red light with a long (microsecond-scale) decay time upon excitation of the probes with a pulse of near-UV light.
Original language | English |
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Pages (from-to) | 4096-4098 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 50 |
Issue number | 31 |
DOIs | |
Publication status | Published - 20 Mar 2014 |
Externally published | Yes |