Base logic: Tests of baseline balance in randomized clinical trials

S. J. Senn

doi:10.3109/10601339509019426

Base logic: Tests of baseline balance in randomized clinical trials

S. J. Senn^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)

Abstract

When a randomized clinical trial has been completed, but before the analysis of the main outcome variable, many trialists compare the treatments groups for balance using tests of significance. This practice is critically examined. 'Ignorance, madam, pure ignorance.' Dr Samuel Johnson replying to a lady who had asked him why he defined 'pastern as the knee of a horse.

Original language	English
Pages (from-to)	171-182
Number of pages	12
Journal	Clinical Research and Regulatory Affairs
Volume	12
Issue number	3
DOIs	https://doi.org/10.3109/10601339509019426
Publication status	Published - 1995
Externally published	Yes

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Base logic: Tests of baseline balance in randomized clinical trials

Abstract

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