Bacterial small RNA makes a big impact for gut colonization

Elena Monzel; Mahesh S. Desai

doi:10.1016/j.chom.2024.10.010

Bacterial small RNA makes a big impact for gut colonization

Elena Monzel
, Mahesh S. Desai^*

^*Corresponding author for this work

Nutrition, Microbiome and Immunity

Research output: Contribution to journal › Comment/debate

1 Citation (Scopus)

Abstract

The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.

Original language	English
Pages (from-to)	1875-1877
Number of pages	3
Journal	Cell Host and Microbe
Volume	32
Issue number	11
DOIs	https://doi.org/10.1016/j.chom.2024.10.010
Publication status	Published - 13 Nov 2024

Keywords

Humans
RNA, Bacterial/genetics
Gastrointestinal Microbiome/genetics
RNA, Small Untranslated/genetics
Gastrointestinal Tract/microbiology
Animals
Dietary Carbohydrates/metabolism
Gene Expression Regulation, Bacterial

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10.1016/j.chom.2024.10.010

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@article{d16f1a73cc4e421ea9a1703f1c3e81b7,

title = "Bacterial small RNA makes a big impact for gut colonization",

abstract = "The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host \& Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.",

keywords = "Humans, RNA, Bacterial/genetics, Gastrointestinal Microbiome/genetics, RNA, Small Untranslated/genetics, Gastrointestinal Tract/microbiology, Animals, Dietary Carbohydrates/metabolism, Gene Expression Regulation, Bacterial",

author = "Elena Monzel and Desai, \{Mahesh S.\}",

note = "Funding: We gratefully acknowledge the support of the Luxembourg National Research Fund (FNR) through BRIDGES grant (22/17426243) to M.S.D., and through the PRIDE DTU (21/16749720) to E.M. We also thank the Fondation du P{\'e}lican de Mie et Pierre Hippert-Faber, under the aegis of the Fondation de Luxembourg for supporting E.M. Publisher Copyright: {\textcopyright} 2024 Elsevier Inc.",

year = "2024",

month = nov,

day = "13",

doi = "10.1016/j.chom.2024.10.010",

language = "English",

volume = "32",

pages = "1875--1877",

journal = "Cell Host and Microbe",

issn = "1931-3128",

publisher = "Cell Press",

number = "11",

}

TY - JOUR

T1 - Bacterial small RNA makes a big impact for gut colonization

AU - Monzel, Elena

AU - Desai, Mahesh S.

N1 - Funding: We gratefully acknowledge the support of the Luxembourg National Research Fund (FNR) through BRIDGES grant (22/17426243) to M.S.D., and through the PRIDE DTU (21/16749720) to E.M. We also thank the Fondation du Pélican de Mie et Pierre Hippert-Faber, under the aegis of the Fondation de Luxembourg for supporting E.M. Publisher Copyright: © 2024 Elsevier Inc.

PY - 2024/11/13

Y1 - 2024/11/13

N2 - The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.

AB - The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.

KW - Humans

KW - RNA, Bacterial/genetics

KW - Gastrointestinal Microbiome/genetics

KW - RNA, Small Untranslated/genetics

KW - Gastrointestinal Tract/microbiology

KW - Animals

KW - Dietary Carbohydrates/metabolism

KW - Gene Expression Regulation, Bacterial

UR - https://www.scopus.com/pages/publications/85208278649

UR - https://pubmed.ncbi.nlm.nih.gov/39541940/

U2 - 10.1016/j.chom.2024.10.010

DO - 10.1016/j.chom.2024.10.010

M3 - Comment/debate

C2 - 39541940

AN - SCOPUS:85208278649

SN - 1931-3128

VL - 32

SP - 1875

EP - 1877

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 11

ER -

Bacterial small RNA makes a big impact for gut colonization

Abstract

Keywords

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