TY - JOUR
T1 - Bacterial small RNA makes a big impact for gut colonization
AU - Monzel, Elena
AU - Desai, Mahesh S.
N1 - Funding:
We gratefully acknowledge the support of the Luxembourg National Research Fund (FNR) through BRIDGES grant (22/17426243) to M.S.D., and through the PRIDE DTU (21/16749720) to E.M. We also thank the Fondation du Pélican de Mie et Pierre Hippert-Faber, under the aegis of the Fondation de Luxembourg for supporting E.M.
Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/11/13
Y1 - 2024/11/13
N2 - The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.
AB - The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.
KW - Humans
KW - RNA, Bacterial/genetics
KW - Gastrointestinal Microbiome/genetics
KW - RNA, Small Untranslated/genetics
KW - Gastrointestinal Tract/microbiology
KW - Animals
KW - Dietary Carbohydrates/metabolism
KW - Gene Expression Regulation, Bacterial
UR - http://www.scopus.com/inward/record.url?scp=85208278649&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/39541940/
U2 - 10.1016/j.chom.2024.10.010
DO - 10.1016/j.chom.2024.10.010
M3 - Comment/debate
C2 - 39541940
AN - SCOPUS:85208278649
SN - 1931-3128
VL - 32
SP - 1875
EP - 1877
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 11
ER -