Asterolloside, a novel enolic saccharide from the sea star Asterias rollestoni Bell

Xian Wen Yang*, Zi Miao, Xiao Ni Ma, Gai Yun Zhang, Andre Steinmetz, Bin Yang, Jun Feng Wang, Juan Liu, Yonghong Liu, Ning Wang

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

The first natural enolic glycoside, asterolloside (1), was isolated from the starfish Asterias rollestoni Bell together with two known tetrasaccharides. The structure of asterolloside was primarily elucidated by analysis of 1D and 2D NMR spectroscopic data. The absolute configuration was unambiguously determined by single-crystal Cu-Kα X-ray diffraction analysis. Asterolloside showed moderate α-glucosidase inhibitory activity with an inhibitory rate of 37.9% at a concentration of 0.12 mg/mL.

Original languageEnglish
Pages (from-to)6174-6176
Number of pages3
JournalTetrahedron Letters
Volume56
Issue number45
DOIs
Publication statusPublished - 4 Sept 2015

Keywords

  • Asterias rollestoni
  • Enolic saccharides
  • Starfish
  • α-Glucosidase

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