TY - JOUR
T1 - Association between the index of nutritional quality and lipid profile in adult women
AU - Abbas Torki, Saheb
AU - Bahadori, Effat
AU - Shekari, Soheila
AU - Fathi, Soroor
AU - Gholamalizadeh, Maryam
AU - Hasanpour Ardekanizadeh, Naeemeh
AU - Aminnezhad, Bahareh
AU - Ahmadzadeh, Mina
AU - Sotoudeh, Mahtab
AU - Shafie, Fatemeh
AU - Rastgoo, Samira
AU - Vahid, Farhad
AU - Doaei, Saeid
N1 - Funding Information:
Funding for this study was provided by Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Publisher Copyright:
© 2022 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd.
PY - 2022/9
Y1 - 2022/9
N2 - Background: Dyslipidaemia is a group of abnormalities that predispose people to heart disease. The index of nutritional quality (INQ) is a tool for qualitative and quantitative nutritional assessment, which has special significance in assessing clinical nutritional problems. The objective of this study was to determine the association between the INQ and lipid profile in adult women. Methods: This was a cross-sectional study on 360 healthy women referring to the nutrition clinic of Shohadaye Tajrish hospital, Tehran, Iran. Calorie and nutrient intake were assessed using a validated food frequency questionnaire. The amount of physical activity was estimated using a validated International Physical Activity Questionnaire. To measure serum lipid levels, 5 ml of venous blood samples was taken from the participants. Results: The results showed a negative association between total cholesterol and the INQ of niacin (B = −0.110, p =.02) and between high-density lipoprotein cholesterol with the INQ of biotin (B = −0.119, p =.01). Also, a positive association was found between triglyceride and the INQ of B6 (B = 0.096, p =.04). The results remained significant after adjusting for body mass index, waist circumference and total energy intake (except for niacin). Conclusions: Findings of the present study suggest that a diet rich in niacin and low in vitamin B6 and biotin may be associated with an improved lipid profile that reduces lipid-related diseases such as fatty liver, metabolic syndrome and cardiovascular disease. Further studies are needed to confirm these findings and to identify the underlying mechanisms.
AB - Background: Dyslipidaemia is a group of abnormalities that predispose people to heart disease. The index of nutritional quality (INQ) is a tool for qualitative and quantitative nutritional assessment, which has special significance in assessing clinical nutritional problems. The objective of this study was to determine the association between the INQ and lipid profile in adult women. Methods: This was a cross-sectional study on 360 healthy women referring to the nutrition clinic of Shohadaye Tajrish hospital, Tehran, Iran. Calorie and nutrient intake were assessed using a validated food frequency questionnaire. The amount of physical activity was estimated using a validated International Physical Activity Questionnaire. To measure serum lipid levels, 5 ml of venous blood samples was taken from the participants. Results: The results showed a negative association between total cholesterol and the INQ of niacin (B = −0.110, p =.02) and between high-density lipoprotein cholesterol with the INQ of biotin (B = −0.119, p =.01). Also, a positive association was found between triglyceride and the INQ of B6 (B = 0.096, p =.04). The results remained significant after adjusting for body mass index, waist circumference and total energy intake (except for niacin). Conclusions: Findings of the present study suggest that a diet rich in niacin and low in vitamin B6 and biotin may be associated with an improved lipid profile that reduces lipid-related diseases such as fatty liver, metabolic syndrome and cardiovascular disease. Further studies are needed to confirm these findings and to identify the underlying mechanisms.
KW - biotin
KW - dyslipidaemia
KW - index of nutritional quality
KW - lipid profile
KW - niacin
KW - nutritional assessment
UR - http://www.scopus.com/inward/record.url?scp=85134198737&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/35856460
U2 - 10.1002/edm2.358
DO - 10.1002/edm2.358
M3 - Article
C2 - 35856460
AN - SCOPUS:85134198737
SN - 2398-9238
VL - 5
JO - Endocrinology, Diabetes and Metabolism
JF - Endocrinology, Diabetes and Metabolism
IS - 5
M1 - e358
ER -