Association between the index of nutritional quality and lipid profile in adult women

Saheb Abbas Torki, Effat Bahadori, Soheila Shekari, Soroor Fathi, Maryam Gholamalizadeh, Naeemeh Hasanpour Ardekanizadeh, Bahareh Aminnezhad, Mina Ahmadzadeh, Mahtab Sotoudeh, Fatemeh Shafie, Samira Rastgoo, Farhad Vahid*, Saeid Doaei*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


Background: Dyslipidaemia is a group of abnormalities that predispose people to heart disease. The index of nutritional quality (INQ) is a tool for qualitative and quantitative nutritional assessment, which has special significance in assessing clinical nutritional problems. The objective of this study was to determine the association between the INQ and lipid profile in adult women. Methods: This was a cross-sectional study on 360 healthy women referring to the nutrition clinic of Shohadaye Tajrish hospital, Tehran, Iran. Calorie and nutrient intake were assessed using a validated food frequency questionnaire. The amount of physical activity was estimated using a validated International Physical Activity Questionnaire. To measure serum lipid levels, 5 ml of venous blood samples was taken from the participants. Results: The results showed a negative association between total cholesterol and the INQ of niacin (B = −0.110, p =.02) and between high-density lipoprotein cholesterol with the INQ of biotin (B = −0.119, p =.01). Also, a positive association was found between triglyceride and the INQ of B6 (B = 0.096, p =.04). The results remained significant after adjusting for body mass index, waist circumference and total energy intake (except for niacin). Conclusions: Findings of the present study suggest that a diet rich in niacin and low in vitamin B6 and biotin may be associated with an improved lipid profile that reduces lipid-related diseases such as fatty liver, metabolic syndrome and cardiovascular disease. Further studies are needed to confirm these findings and to identify the underlying mechanisms.

Original languageEnglish
Article numbere358
JournalEndocrinology, Diabetes and Metabolism
Issue number5
Early online date20 Jul 2022
Publication statusPublished - Sept 2022


  • biotin
  • dyslipidaemia
  • index of nutritional quality
  • lipid profile
  • niacin
  • nutritional assessment


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