Antibacterial activity of the soil-bound antimicrobials oxytetracycline and ofloxacin

Feng Jiao Peng, Li Jun Zhou, Guang Guo Ying*, You Sheng Liu, Jian Liang Zhao

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Abstract

Soil contamination of antimicrobials has become an increasing concern because of the potential risks to the soil microbial ecosystem and human health. The present study investigated sorption and desorption behaviors of oxytetracycline (OTC) and ofloxacin (OFL) in 3 typical soils (A, B, and C), and evaluated the antibacterial activity of soil-adsorbed compounds to a pure sensitive strain Escherichia coli ATCC 25922. The results showed different sorption and desorption behaviors of OTC and OFL in the 3 soils, behaviors that were mainly influenced by soil organic matter content and cation exchange capacity (CEC) as well as pH value. In addition, complexation and cation-exchange reactions were shown to be the main sorption mechanisms. Strong adsorption was found in soil B (with a high organic matter content) and in soil C (with high CEC), whereas enhanced desorption was observed in soil A (with low organic matter content). The results also demonstrated that soil-bound antimicrobials retained antibacterial activity toward E. coli. Opposite patterns of antibacterial activity were found for the 2 antimicrobials in the 3 soils: A>B>C for OFL; and C>B>A for OTC. This finding suggests that soil-bound antimicrobials could still exert selective pressure on soil bacteria although less effectively in comparison with the dissolved forms. Environ Toxicol Chem 2014;33:776-783.

Original languageEnglish
Pages (from-to)776-783
Number of pages8
JournalEnvironmental Toxicology and Chemistry
Volume33
Issue number4
DOIs
Publication statusPublished - Apr 2014
Externally publishedYes

Keywords

  • Adsorption
  • Antibacterial activity
  • Desorption
  • Hysteresis
  • Ofloxacin
  • Oxytetracycline

Fingerprint

Dive into the research topics of 'Antibacterial activity of the soil-bound antimicrobials oxytetracycline and ofloxacin'. Together they form a unique fingerprint.

Cite this