Anal canal cancer: In the era of intensity-modulated radiotherapy, outstanding issues

D. Peiffert; A. S. Baumann; A. A. Serre; V. Vendrely; N. Rouard; J. C. Faivre; G. Vogin

doi:10.1016/j.canrad.2018.07.131

Anal canal cancer: In the era of intensity-modulated radiotherapy, outstanding issues

D. Peiffert^*, A. S. Baumann, A. A. Serre, V. Vendrely, N. Rouard, J. C. Faivre, G. Vogin

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

1 Citation (Scopus)

Abstract

Intensity-modulated radiotherapy makes possible to optimize the irradiation and spare normal tissues. The toxicity remains important with concomitant chemotherapy often associated. The improvement of MRI and PET-CT define more precisely the target volumes, which need a higher dose, but necessitates to respect the rules of contouring. The treatment is uniform whatever the stage but should be individualized based on clinical stage and tumor response. New paradigms concern biology, staging, volumes and doses, fractionation and combined treatments.

Original language	English
Pages (from-to)	509-514
Number of pages	6
Journal	Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Volume	22
Issue number	6-7
DOIs	https://doi.org/10.1016/j.canrad.2018.07.131
Publication status	Published - Oct 2018
Externally published	Yes

Keywords

Anal cancer
Brachytherapy
Chemoradiotherapy
Clinical trials
Delineation
IMRT

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10.1016/j.canrad.2018.07.131

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title = "Anal canal cancer: In the era of intensity-modulated radiotherapy, outstanding issues",

abstract = "Intensity-modulated radiotherapy makes possible to optimize the irradiation and spare normal tissues. The toxicity remains important with concomitant chemotherapy often associated. The improvement of MRI and PET-CT define more precisely the target volumes, which need a higher dose, but necessitates to respect the rules of contouring. The treatment is uniform whatever the stage but should be individualized based on clinical stage and tumor response. New paradigms concern biology, staging, volumes and doses, fractionation and combined treatments.",

keywords = "Anal cancer, Brachytherapy, Chemoradiotherapy, Clinical trials, Delineation, IMRT",

author = "D. Peiffert and Baumann, {A. S.} and Serre, {A. A.} and V. Vendrely and N. Rouard and Faivre, {J. C.} and G. Vogin",

note = "Publisher Copyright: {\textcopyright} 2018 Soci{\'e}t{\'e} fran{\c c}aise de radioth{\'e}rapie oncologique (SFRO)",

year = "2018",

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doi = "10.1016/j.canrad.2018.07.131",

language = "English",

volume = "22",

pages = "509--514",

journal = "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique",

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number = "6-7",

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TY - JOUR

T1 - Anal canal cancer

T2 - In the era of intensity-modulated radiotherapy, outstanding issues

AU - Peiffert, D.

AU - Baumann, A. S.

AU - Serre, A. A.

AU - Vendrely, V.

AU - Rouard, N.

AU - Faivre, J. C.

AU - Vogin, G.

PY - 2018/10

Y1 - 2018/10

N2 - Intensity-modulated radiotherapy makes possible to optimize the irradiation and spare normal tissues. The toxicity remains important with concomitant chemotherapy often associated. The improvement of MRI and PET-CT define more precisely the target volumes, which need a higher dose, but necessitates to respect the rules of contouring. The treatment is uniform whatever the stage but should be individualized based on clinical stage and tumor response. New paradigms concern biology, staging, volumes and doses, fractionation and combined treatments.

AB - Intensity-modulated radiotherapy makes possible to optimize the irradiation and spare normal tissues. The toxicity remains important with concomitant chemotherapy often associated. The improvement of MRI and PET-CT define more precisely the target volumes, which need a higher dose, but necessitates to respect the rules of contouring. The treatment is uniform whatever the stage but should be individualized based on clinical stage and tumor response. New paradigms concern biology, staging, volumes and doses, fractionation and combined treatments.

KW - Anal cancer

KW - Brachytherapy

KW - Chemoradiotherapy

KW - Clinical trials

KW - Delineation

KW - IMRT

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DO - 10.1016/j.canrad.2018.07.131

M3 - Short survey

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AN - SCOPUS:85052724541

SN - 1278-3218

VL - 22

SP - 509

EP - 514

JO - Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

JF - Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

IS - 6-7

ER -

Anal canal cancer: In the era of intensity-modulated radiotherapy, outstanding issues

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