Abstract
A rubella outbreak involving 1900 cases was recorded in the Federation of Bosnia and Herzegovina between mid-December 2009 and the end of May 2010. Sera from 389 suspected rubella cases were examined for the presence of rubella-specific IgM and IgG antibodies. A total of 32 throat swabs from suspected rubella cases were tested by RT-PCR and were used to attempt virus isolation. Most patients (945/1900, 49·73%) had never received rubella vaccination or had an unknown vaccination status (563/1900, 29·63%). About 45% (178/389) of suspected rubella patients were IgM positive. From 13 of the throat swabs a virus isolate and E1 gene sequences attributed to genotype 2B were obtained. The rubella outbreak was due to failure to vaccinate during the war period (1992-1995) and emphasizes the need for additional vaccination opportunities.
Original language | English |
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Pages (from-to) | 447-453 |
Number of pages | 7 |
Journal | Epidemiology and Infection |
Volume | 140 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2012 |
Keywords
- Bosnia and Herzegovina
- genotype
- outbreak
- rubella
- vaccination