Adeno-Parovirus chimera with enhanced oncolytical potential

Nazim El-Andaloussi; Antonio Marchini; Jean Rommelaere

Adeno-Parovirus chimera with enhanced oncolytical potential

Nazim El-Andaloussi (Inventor)
, Antonio Marchini (Inventor)
, Jean Rommelaere (Inventor)

Research output: Patent

Abstract

Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of El and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.

Original language	English
IPC	WO 2013/004396
Publication status	Published - 1 Oct 2013
Externally published	Yes

Cite this

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title = "Adeno-Parovirus chimera with enhanced oncolytical potential",

abstract = "Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of El and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.",

author = "Nazim El-Andaloussi and Antonio Marchini and Jean Rommelaere",

year = "2013",

month = oct,

day = "1",

language = "English",

type = "Patent",

note = "WO 2013/004396",

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TY - PAT

T1 - Adeno-Parovirus chimera with enhanced oncolytical potential

AU - El-Andaloussi, Nazim

AU - Marchini, Antonio

AU - Rommelaere, Jean

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of El and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.

AB - Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of El and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.

M3 - Patent

ER -

Adeno-Parovirus chimera with enhanced oncolytical potential

Abstract

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