Adeno-Parovirus chimera with enhanced oncolytical potential

Nazim El-Andaloussi (Inventor), Antonio Marchini (Inventor), Jean Rommelaere (Inventor)

Research output: Patent


Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of El and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.
Original languageEnglish
IPCWO 2013/004396
Publication statusPublished - 1 Oct 2013
Externally publishedYes


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