TY - JOUR
T1 - A pro-inflammatory diet increases the likelihood of obesity and overweight in adolescent boys
T2 - A case-control study
AU - Vahid, Farhad
AU - Bourbour, Fatemeh
AU - Gholamalizadeh, Maryam
AU - Shivappa, Nitin
AU - Hébert, James R.
AU - Babakhani, Khatereh
AU - Mosavi Jarrahi, Alireza
AU - Mirzaei Dahka, Samaneh
AU - Doaei, Saeid
N1 - Funding Information:
Funding for this study was provided by Shahid Beheshti University of Medical Sciences
Publisher Copyright:
© 2020 The Author(s).
PY - 2020/4/7
Y1 - 2020/4/7
N2 - Background: Obesity and Overweight at an early age can contribute with many chronic diseases such as cancers, diabetes and cardiovascular diseases. Diet-related inflammation is one of the most important underlying mechanisms that may has a key role in obesity and overweight. This paper aimed to compare the dietary inflammatory index (DII®) in normal weight and overweight adolescent boys. Methods: A total of 535 adolescent boys (214 cases were overweight and obese and 321 controls with normal weight) participated in this study from two schools in Tehran, Iran. The student's weight and body composition were measured using a Bio-Impedance Analyzer (BIA) scale. A validated semi-quantitative Food Frequency Questionnaire (FFQ) was used to assess dietary inflammatory index. Results: Results obtained from modeling DII® as a continuous variable identified a positive association between DII® and obesity (OR = 1.08, CI 1.01-1.16). After multivariable adjustment, subjects with DII® > 0.02 had at 1.5 times higher odds of obesity and overweight compared to subjects with DII® ≤ 0.02 (OR = 1.52; CI 1.04-2.22). Conclusion: Our study indicated the importance of dietary-induced inflammation in the obesity and overweight during adolescence. Therefore, advising adolescent to consume diet with lower DII® with more fruits and vegetables, rich sources of fiber, flavonoids, zinc, magnesium and selenium and avoiding the consumption of saturated fatty acids (SFA), trans-fatty acids, and cholesterol may support a healthy weight.
AB - Background: Obesity and Overweight at an early age can contribute with many chronic diseases such as cancers, diabetes and cardiovascular diseases. Diet-related inflammation is one of the most important underlying mechanisms that may has a key role in obesity and overweight. This paper aimed to compare the dietary inflammatory index (DII®) in normal weight and overweight adolescent boys. Methods: A total of 535 adolescent boys (214 cases were overweight and obese and 321 controls with normal weight) participated in this study from two schools in Tehran, Iran. The student's weight and body composition were measured using a Bio-Impedance Analyzer (BIA) scale. A validated semi-quantitative Food Frequency Questionnaire (FFQ) was used to assess dietary inflammatory index. Results: Results obtained from modeling DII® as a continuous variable identified a positive association between DII® and obesity (OR = 1.08, CI 1.01-1.16). After multivariable adjustment, subjects with DII® > 0.02 had at 1.5 times higher odds of obesity and overweight compared to subjects with DII® ≤ 0.02 (OR = 1.52; CI 1.04-2.22). Conclusion: Our study indicated the importance of dietary-induced inflammation in the obesity and overweight during adolescence. Therefore, advising adolescent to consume diet with lower DII® with more fruits and vegetables, rich sources of fiber, flavonoids, zinc, magnesium and selenium and avoiding the consumption of saturated fatty acids (SFA), trans-fatty acids, and cholesterol may support a healthy weight.
KW - Adolescence
KW - Diet
KW - Inflammation
KW - Obesity
KW - Overweight
UR - http://www.scopus.com/inward/record.url?scp=85083108141&partnerID=8YFLogxK
U2 - 10.1186/s13098-020-00536-0
DO - 10.1186/s13098-020-00536-0
M3 - Article
C2 - 32292493
AN - SCOPUS:85083108141
SN - 1758-5996
VL - 12
SP - 29
JO - Diabetology and Metabolic Syndrome
JF - Diabetology and Metabolic Syndrome
IS - 1
M1 - 29
ER -