A comment on interim analyses in crossover trials

Andrew P. Grieve; Stephen Senn; R. J. Cook

doi:10.2307/2532866

A comment on interim analyses in crossover trials

Andrew P. Grieve^*
, Stephen Senn
, R. J. Cook

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.

Original language	English
Pages (from-to)	1515-1520
Number of pages	6
Journal	Biometrics
Volume	52
Issue number	4
DOIs	https://doi.org/10.2307/2532866
Publication status	Published - Dec 1996
Externally published	Yes

Keywords

Crossover trials
sequential analysis

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10.2307/2532866

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title = "A comment on interim analyses in crossover trials",

abstract = "In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.",

keywords = "Crossover trials, sequential analysis",

author = "Grieve, \{Andrew P.\} and Stephen Senn and Cook, \{R. J.\}",

year = "1996",

month = dec,

doi = "10.2307/2532866",

language = "English",

volume = "52",

pages = "1515--1520",

journal = "Biometrics",

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T1 - A comment on interim analyses in crossover trials

AU - Grieve, Andrew P.

AU - Senn, Stephen

AU - Cook, R. J.

PY - 1996/12

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N2 - In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.

AB - In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.

KW - Crossover trials

KW - sequential analysis

UR - https://www.scopus.com/pages/publications/0030451153

U2 - 10.2307/2532866

DO - 10.2307/2532866

M3 - Article

C2 - 9019232

AN - SCOPUS:0030451153

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VL - 52

SP - 1515

EP - 1520

JO - Biometrics

JF - Biometrics

IS - 4

ER -

A comment on interim analyses in crossover trials

Abstract

Keywords

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