A comment on interim analyses in crossover trials

Andrew P. Grieve; Stephen Senn; R. J. Cook

doi:10.2307/2532866

A comment on interim analyses in crossover trials

Andrew P. Grieve^*, Stephen Senn, R. J. Cook

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.

Original language	English
Pages (from-to)	1515-1520
Number of pages	6
Journal	Biometrics
Volume	52
Issue number	4
DOIs	https://doi.org/10.2307/2532866
Publication status	Published - Dec 1996
Externally published	Yes

Keywords

Crossover trials
sequential analysis

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10.2307/2532866

Cite this

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title = "A comment on interim analyses in crossover trials",

abstract = "In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.",

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year = "1996",

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AU - Cook, R. J.

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AB - In a recent issue of Biometrics, Cook (1995, Biometrics, 51, 932-945) considered the possibility of applying sequential analysis to 2 x 2 crossover trials and made a comparison with more conventional approaches. We believe this comparison to be misleading in a number of respects.

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KW - sequential analysis

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JO - Biometrics

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A comment on interim analyses in crossover trials

Abstract

Keywords

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