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Role for the Itaconate/Nrf2 axis in metabolic and epigenetic reprogramming of neonatal macrophages
Meiser, Johannes
(PI)
Ohl, Kim
(PI)
Cancer Metabolism Group
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Medicine & Life Sciences
itaconic acid
100%
Macrophages
62%
Epigenomics
53%
Phenotype
28%
Newborn Infant
27%
Metabolic Networks and Pathways
24%
Monocytes
19%
Metabolic Flux Analysis
19%
Immune System
19%
Anti-Inflammatory Agents
17%
Neonatal Sepsis
15%
Cytokines
14%
Macrophage Activation
13%
Chromatin Immunoprecipitation
13%
Acetylation
12%
Glycolysis
12%
Formal Social Control
12%
DNA Methylation
11%
Plastics
11%
Oxidation-Reduction
11%
Histones
11%
Innate Immunity
11%
Knockout Mice
11%
Methylation
10%
Lactic Acid
10%
Chromatin
10%
Respiration
9%
Sepsis
9%
Reactive Oxygen Species
9%
Genome
8%
Bacteria
8%
Infections
5%