Relationship between dietary exposure to mixtures of persistent organic pollutants and type 2 diabetes: the modulating potential of diet

Type 2 diabetes is a major health concern, often leading to several cardiometabolic comorbidities. The disease can be modulated by dietary choices, but also via the intake of persistent pollutants with food. This project will study the association of various classes of persistent organic pollutants and dietary patterns with the risk of type 2 diabetes, as well as their interactions. For this purpose, participants of a multi-country cohort study will be investigated for their intake of various persistent organic pollutants and dietary patterns by various indices, food and nutrient intake based on food frequency questionnaires.

This study will reveal the effects of combined exposure of environmental pollutants and diet in relation to type 2 diabetes, and to which extent these main contributors to type 2 diabetes can aggravate or compensate one another.