Overweight and obesity in paediatric population in Luxembourg. Pollutants and micronutrients interrelations.

Overweight and obesity have been associated with an increased risk of cardiometabolic complications in children, in particular in the presence of visceral adipose tissue (VAT) storage. VAT was also associated with high concentrations of Persistent Organic Pollutants (POPs), acting as endocrine disruptors, with negative effects on cardiometabolic health, oxidative stress and inflammation in adults. Some animal studies highlighted that, in the presence of obesogenic environment, certain micronutrients and phytochemicals appear to act as protectors from a potential hypertrophy within the adipocytes.
The purpose of this project was to investigate the relationship between VAT and inflammatory status and oxidative stress in youth with overweight and obesity; and whether this status (VAT, oxidative stress) is associated with an imbalance of micronutrients / phytochemicals intake and POPs exposure.