Tumor growth and dissemination is one of the most important issues in cancer biology. Chemokines are a superfamily of chemo-attract ant cytokines playing critical roles in these events. The biological effects of chemokines are mediated through seven transmembrane receptors coupled to G proteins. Chemokine receptors are usually coupled to Gi but may alsotrigger alternative signalling through β-arrestins. Tumor and stromal cells express diverse chemokines and chemokine receptors.
|Effective start/end date
|1/10/15 → 31/07/18
- FNRS - Fonds National de la Recherche Scientifique: €117,689.00
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