Expression and functional characterization of the CXCR3-CXCR7heterodimer in glioblastoma

Project Details


Tumor growth and dissemination is one of the most important issues in cancer biology. Chemokines are a superfamily of chemo-attract ant cytokines playing critical roles in these events. The biological effects of chemokines are mediated through seven transmembrane receptors coupled to G proteins. Chemokine receptors are usually coupled to Gi but may alsotrigger alternative signalling through β-arrestins. Tumor and stromal cells express diverse chemokines and chemokine receptors.
Effective start/end date1/10/1531/07/18


  • FNRS - Fonds National de la Recherche Scientifique: €117,689.00


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