Dietary fiber, markers of inflammation and gut microbiota

It has been demonstrated that a higher fiber intake is health beneficial, acting via anti-inflammatory and immune related pathways, which are mediated by the gut microbiota. However, it is not clear to what extent the effects observed depend on the genetic background, which may be an important consideration for explaining health related effects of dietary patterns and interventions. This PhD project builds on the already conducted LUX-FiCo study, investigating the effects of short-term intervention of dietary fiber on the gut microbiota and the immune system. In the current DTU project, a novel and unique aspect will be whole genome analyses of the healthy volunteers participating in the above interventional study.