Benefit of physical activity on hormonal homeostasis and hormonal disruption induced by exposure to chemical pollutants

As physical activity helps regulate hormones, it may play a role in hormone-related health issues such as stress or weight gain. Using data from a Luxembourg population study, the PhD student will compute new wearable-specific indicators of the physical behaviour to capture all dimensions of the 24h movement behaviour. Endocrine disrupting chemicals and hormonal profiles of study participants will be analysed based on their hair samples. The moderation effect of the physical behaviour on hormonal profiles will be investigated in the context of exposure to the endocrine disrupting chemicals.

This PhD project will strive to describe the multidimensional physical behaviour profile of an individual, explore its role in the causal pathway relating the endocrine disrupting chemicals to hormonal, and shape future evidence-based preventive measures.