Research output per year
Research output per year
- 13 results
Search results
-
2025
Blocking lactate: kick T cells when they are down
Horkova, V., Everts, B. & Brenner, D., 19 Mar 2025, In: Immunometabolism (United States). 7, 2, 3 p., e00059.Research output: Contribution to journal › Comment/debate
Open Access -
2024
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
Bonetti, L., Horkova, V., Grusdat, M., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Binsfeld, C., Verschueren, C., Spath, S., Ewen, A., Koncina, E., Gérardy, J. J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Fan, Y. T. & Chen, Y. & 8 others, , 6 Aug 2024, In: Cell Metabolism. 36, 8, p. 1726-1744.e10Research output: Contribution to journal › Article › Research › peer-review
Open Access12 Citations (Scopus) -
2023
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y. & Harris, I. S. & 7 others, , 7 Jul 2023, (bioRxiv).Research output: Working paper › Preprint
Open Access -
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
Soriano-Baguet, L., Grusdat, M., Kurniawan, H., Benzarti, M., Binsfeld, C., Ewen, A., Longworth, J., Bonetti, L., Guerra, L., Franchina, D. G., Kobayashi, T., Horkova, V., Verschueren, C., Helgueta, S., Gérard, D., More, T. H., Henne, A., Dostert, C., Farinelle, S. & Lesur, A. & 7 others, , 28 Mar 2023, In: Cell Reports. 42, 3, 112153.Research output: Contribution to journal › Article › Research › peer-review
Open Access18 Citations (Scopus) -
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells
Horkova, V., Drobek, A., Paprckova, D., Niederlova, V., Prasai, A., Uleri, V., Glatzova, D., Kraller, M., Cesnekova, M., Janusova, S., Salyova, E., Tsyklauri, O., Kadlecek, T. A., Krizova, K., Platzer, R., Schober, K., Busch, D. H., Weiss, A., Huppa, J. B. & Stepanek, O., Jan 2023, In: Nature Immunology. 24, 1, p. 174-185 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access23 Citations (Scopus) -
2022
Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections
Paprckova, D., Niederlova, V., Moudra, A., Drobek, A., Pribikova, M., Janusova, S., Schober, K., Neuwirth, A., Michalik, J., Huranova, M., Horkova, V., Cesnekova, M., Simova, M., Prochazka, J., Balounova, J., Busch, D. H., Sedlacek, R., Schwarzer, M. & Stepanek, O., 6 Oct 2022, In: Frontiers in Immunology. 13, 1009198.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
2021
A LoCK at the T cell dock
Horkova, V. & Stepanek, O., 4 Jun 2021, In: Science. 372, 6546, p. 1038-1039 2 p.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus
Karimi, M. M., Guo, Y., Cui, X., Pallikonda, H. A., Horková, V., Wang, Y. F., Gil, S. R., Rodriguez-Esteban, G., Robles-Rebollo, I., Bruno, L., Georgieva, R., Patel, B., Elliott, J., Dore, M. H., Dauphars, D., Krangel, M. S., Lenhard, B., Heyn, H., Fisher, A. G. & Štěpánek, O. & 1 others, , 1 Dec 2021, In: Nature Communications. 12, 1, 99.Research output: Contribution to journal › Article › Research › peer-review
Open Access30 Citations (Scopus) -
2020
Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
Horkova, V., Drobek, A., Mueller, D., Gubser, C., Niederlova, V., Wyss, L., King, C. G., Zehn, D. & Stepanek, O., 4 Feb 2020, In: Cell Reports. 30, 5, p. 1504-1514.e7Research output: Contribution to journal › Article › Research › peer-review
Open Access30 Citations (Scopus) -
2019
CD45 functions as a signaling gatekeeper in T cells
Courtney, A. H., Shvets, A. A., Lu, W., Griffante, G., Mollenauer, M., Horkova, V., Lo, W. L., Yu, S., Stepanek, O., Chakraborty, A. K. & Weiss, A., 2019, In: Science Signaling. 12, 604, eaaw8151.Research output: Contribution to journal › Article › Research › peer-review
Open Access89 Citations (Scopus) -
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination
Lo, W. L., Shah, N. H., Rubin, S. A., Zhang, W., Horkova, V., Fallahee, I. R., Stepanek, O., Zon, L. I., Kuriyan, J. & Weiss, A., 1 Nov 2019, In: Nature Immunology. 20, 11, p. 1481-1493 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access56 Citations (Scopus) -
2018
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
Lo, W. L., Shah, N. H., Ahsan, N., Horkova, V., Stepanek, O., Salomon, A. R., Kuriyan, J. & Weiss, A., 1 Jul 2018, In: Nature Immunology. 19, 7, p. 733-741 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access114 Citations (Scopus) -
Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells
Drobek, A., Moudra, A., Mueller, D., Huranova, M., Horkova, V., Pribikova, M., Ivanek, R., Oberle, S., Zehn, D., McCoy, K. D., Draber, P. & Stepanek, O., 13 Jul 2018, In: EMBO Journal. 37, 14, e98518.Research output: Contribution to journal › Article › Research › peer-review
Open Access59 Citations (Scopus)