Research output

Research output per year 2011 2014 2015 2016 2017 2018 2019 2020 2021 2022

• 33 Article
• 3 Abstract
• 1 Conference contribution
• 1 Meeting Abstract

Research output per year

Research output per year

Search results

• 2022

  Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

  Yabo, Y. A., Pires-Afonso, Y., Moreno-Sanchez, P. M., Oudin, A., Kaoma, T., Nazarov, P. . V., Skupin, A., Niclou, S. P., Michelucci, A. & Golebiewska, A., 5 Sept 2022, In: Neuro-Oncology. 24, Suppl.2, p. ii13

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

• Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease

  Garcia, P., Jürgens-Wemheuer, W., Uriarte Huarte, O., Michelucci, A., Masuch, A., Brioschi, S., Weihofen, A., Koncina, E., Coowar, D., Heurtaux, T., Glaab, E., Balling, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N., Biber, K., & 5 othersKleine-Borgmann, F., Mittelbronn, M., Ostaszewski, M., Schmit, K. J. & Buttini, M., May 2022, In: GLIA. 70, 5, p. 935-960 26 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • alpha-Synuclein 100%
  • Parkinson Disease 69%
  • Microglia 28%
  • Brain 27%
  • Synucleins 21%
  12 Citations (Scopus)
• 2021

  Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

  Larrue, C., Guiraud, N., Mouchel, P. L., Dubois, M., Farge, T., Gotanègre, M., Bosc, C., Saland, E., Nicolau-Travers, M. L., Sabatier, M., Serhan, N., Sahal, A., Boet, E., Mouche, S., Heydt, Q., Aroua, N., Stuani, L., Kaoma, T., Angenendt, L., Mikesch, J. H., & 5 othersSchliemann, C., Vergez, F., Tamburini, J., Récher, C. & Sarry, J. E., 18 Jan 2021, In: Nature Communications. 12, 1, 422.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Calcitonin Receptor-Like Protein 100%
  • Adrenomedullin Receptors 98%
  • leukemias 88%
  • Calcitonin 88%
  • Myeloid Cells 62%
  17 Citations (Scopus)

• A New Synuclein-Transgenic Mouse Model for Early Parkinson’s Reveals Molecular Features of Preclinical Disease

  Hendrickx, D. M., Garcia, P., Ashrafi, A., Sciortino, A., Schmit, K. J., Kollmus, H., Nicot, N., Kaoma, T., Vallar, L., Buttini, M. & Glaab, E., Feb 2021, In: Molecular Neurobiology. 58, 2, p. 576-602 27 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Synucleins 100%
  • Transgenic Mice 58%
  • Parkinson Disease 55%
  • Disease Progression 31%
  • Mesencephalon 27%
  3 Citations (Scopus)

• Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers

  Bejjani, F., Tolza, C., Boulanger, M., Downes, D., Romero, R., Maqbool, M. A., Zine El Aabidine, A., Andrau, J. C., Lebre, S., Brehelin, L., Parrinello, H., Rohmer, M., Kaoma, T., Vallar, L., Hughes, J. R., Zibara, K., Lecellier, C. H., Piechaczyk, M. & Jariel-Encontre, I., 18 Mar 2021, In: Nucleic Acids Research. 49, 5, p. 2488-2508 21 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Triple Negative Breast Neoplasms 100%
  • Chromatin 73%
  • Transcription Factor AP-1 55%
  • Genes 33%
  • fos-related antigen 1 30%
  7 Citations (Scopus)

• Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia

  Bosc, C., Saland, E., Bousard, A., Gadaud, N., Sabatier, M., Cognet, G., Farge, T., Boet, E., Gotanègre, M., Aroua, N., Mouchel, P. L., Polley, N., Larrue, C., Kaphan, E., Picard, M., Sahal, A., Jarrou, L., Tosolini, M., Rambow, F., Cabon, F., & 20 othersNicot, N., Poillet-Perez, L., Wang, Y., Su, X., Fovez, Q., Kluza, J., Argüello, R. J., Mazzotti, C., Avet-Loiseau, H., Vergez, F., Tamburini, J., Fournié, J. J., Tiong, I. S., Wei, A. H., Kaoma, T., Marine, J. C., Récher, C., Stuani, L., Joffre, C. & Sarry, J. E., Nov 2021, In: Nature Cancer. 2, 11, p. 1204-1223 20 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • venetoclax 100%
  • Cytarabine 71%
  • Acute Myeloid Leukemia 60%
  • Myeloid Cells 27%
  • Azacitidine 23%
  11 Citations (Scopus)

• Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

  Stuani, L., Sabatier, M., Saland, E., Cognet, G., Poupin, N., Bosc, C., Castelli, F. A., Gales, L., Turtoi, E., Montersino, C., Farge, T., Boet, E., Broin, N., Larrue, C., Baran, N., Cisse, M. Y., Conti, M., Loric, S., Kaoma, T., Hucteau, A., & 33 othersZavoriti, A., Sahal, A., Mouchel, P. L., Gotanègre, M., Cassan, C., Fernando, L., Wang, F., Hosseini, M., Chu-Van, E., Cam, L. L., Carroll, M., Selak, M. A., Vey, N., Castellano, R., Fenaille, F., Turtoi, A., Cazals, G., Bories, P., Gibon, Y., Nicolay, B., Ronseaux, S., Marszalek, J. R., Takahashi, K., DiNardo, C. D., Konopleva, M., Pancaldi, V., Collette, Y., Bellvert, F., Jourdan, F., Linares, L. K., Recher, C., Portais, J. C. & Sarry, J. E., 3 May 2021, In: Journal of Experimental Medicine. 218, 5, e20200924.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Acute Myeloid Leukemia 100%
  • Methylation 47%
  • Electron Transport Complex I 36%
  • Peroxisome Proliferator-Activated Receptors 31%
  • Mutation 29%
  26 Citations (Scopus)
• 2020

  Deconvolution of “big data” in cancer genomics: from pancancer level to single cells

  Chepeleva, M., Wang, Y., Kakoichankava, A., Muller, A., Kaoma, T. & Nazarov, P. V., 9 Jul 2020, Computer Technologies and Data Analysis (CTDA'2020) : Materials of II International Scientific-Practical Conference, Minsk, 23-24 April, 2020. Bishkek, V. A. & Skakun, V. (eds.). Minsk: BSU, p. 7-11 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

  • cancer 100%
  • cells 57%

• Extracellular atp and cd39 activate camp-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia

  Aroua, N., Boet, E., Ghisi, M., Nicolau-Travers, M. L., Saland, E., Gwilliam, R., de Toni, F., Hosseini, M., Mouchel, P. L., Farge, T., Bosc, C., Stuani, L., Sabatier, M., Mazed, F., Larrue, C., Jarrou, L., Gandarillas, S., Bardotti, M., Picard, M., Syrykh, C., & 13 othersLaurent, C., Gotanègre, M., Bonnefoy, N., Bellvert, F., Portais, J. C., Nicot, N., Azuaje, F., Kaoma, T., Joffre, C., Tamburini, J., Récher, C., Vergez, F. & Sarry, J. E., 2020, In: Cancer Discovery. 10, 10, p. 1544-1565 22 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • Cytarabine 100%
  • Acute Myeloid Leukemia 83%
  • ectoATPase 42%
  • Myeloid Cells 29%
  • Organelle Biogenesis 18%
  21 Citations (Scopus)

• Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software

  Decamps, C., Privé, F., Bacher, R., Jost, D., Waguet, A., Achard, S., Amblard, E., Bacher, R., Bergmann, F., Blum, M., Blum, Y., Bottaz-Bosson, G., Broseus, L., Chuffart, F., Decamps, C., Devijver, E., Durif, G., Feofanov, V., Houseman, E. A., Gallopin, M., & 25 othersJedynak, P., Jonchere, V., Van De Geer, E., Jumentier, B., Kaoma, T., Lurie, E., Lutsik, P., Markowski, J., Melnykova, A., Merlevede, J., Nazarov, P., Nguyen, N. H., Permiakova, O., Privé, F., Richard, M., Rolland, M., Scherer, M., Spill, Y., Houseman, E. A., Lurie, E., Lutsik, P., Milosavljevic, A., Scherer, M., Blum, M. G. B. & Richard, M., 13 Jan 2020, In: BMC Bioinformatics. 21, 1, 16.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • DNA Methylation 100%
  • Comparative Analysis 72%
  • Deconvolution 70%
  • Pipeline 69%
  • Quantification 66%
  20 Citations (Scopus)

• Machine learning-assisted neurotoxicity prediction in human midbrain organoids

  Monzel, A. S., Hemmer, K., Kaoma, T., Smits, L. M., Bolognin, S., Lucarelli, P., Rosety, I., Zagare, A., Antony, P., Nickels, S. L., Krueger, R., Azuaje, F. & Schwamborn, J. C., Jun 2020, In: Parkinsonism and Related Disorders. 75, p. 105-109 5 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Organoids 100%
  • Machine Learning 86%
  • Mesencephalon 79%
  • Parkinson Disease 63%
  • Oxidopamine 43%
  20 Citations (Scopus)

• Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

  Golebiewska, A., Hau, A. C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., Michelucci, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., Azuaje, F., De Falco, A., Flies, B., Richart, L., & 21 othersPoovathingal, S., Arns, T., Grzyb, K., Mock, A., Herold-Mende, C., Steino, A., Brown, D., May, P., Miletic, H., Malta, T. M., Noushmehr, H., Kwon, Y. J., Jahn, W., Klink, B., Tanner, G., Stead, L. F., Mittelbronn, M., Skupin, A., Hertel, F., Bjerkvig, R. & Niclou, S. P., Dec 2020, In: Acta Neuropathologica. 140, 6, p. 919-949 31 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Organoids 100%
  • Glioma 70%
  • Heterografts 68%
  • Temozolomide 18%
  • Dianhydrogalactitol 14%
  41 Citations (Scopus)

• Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz

  Scherer, M., Nazarov, P. V., Toth, R., Sahay, S., Kaoma, T., Maurer, V., Vedeneev, N., Plass, C., Lengauer, T., Walter, J. & Lutsik, P., 1 Oct 2020, In: Nature Protocols. 15, 10, p. 3240-3263 24 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • DNA Methylation 100%
  • Epigenome 42%
  • Methylation 30%
  • DNA Fingerprinting 21%
  • Human Development 18%
  12 Citations (Scopus)
• 2019

  Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas

  Zeiner, P. S., Preusse, C., Golebiewska, A., Zinke, J., Iriondo, A., Muller, A., Kaoma, T., Filipski, K., Müller-Eschner, M., Bernatz, S., Blank, A. E., Baumgarten, P., Ilina, E., Grote, A., Hansmann, M. L., Verhoff, M. A., Franz, K., Feuerhake, F., Steinbach, J. P., Wischhusen, J., & 4 othersStenzel, W., Niclou, S. P., Harter, P. N. & Mittelbronn, M., Jul 2019, In: Brain Pathology. 29, 4, p. 513-529 17 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Microglia 100%
  • Glioma 90%
  • Macrophages 68%
  • Glioblastoma 29%
  • Survival 16%
  63 Citations (Scopus)

• Establishing personalized treatment options for recurrent high-grade gliomas

  Hau, A-C., Houben, L., Klein, E., Oudin, A., Stieber, D., Flies, B., Kaoma, T., Azuaje, F., Fritah, S., Bjerkvig, R., Mittelbronn, M., Hertel, F., Golebiewska, A. & Niclou, S., Nov 2019, p. 97-98.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Hub genes in a pan-cancer co-expression network show potential for predicting drug responses

  Azuaje, F., Kaoma Mukendi, T., Jeanty, C., Nazarov, P. V., Muller, A., Kim, S. Y., Dittmar, G., Golebiewska, A. & Niclou, S. P., 5 Mar 2019, In: F1000Research. 7, 1906.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Drug 100%
  • Pharmaceutical Preparations 78%
  • Genes 76%
  • Neoplasms 61%
  • Datasets 37%
  2 Citations (Scopus)

• Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia

  Larrue, C., Heydt, Q., Saland, E., Boutzen, H., Kaoma, T., Sarry, J. E., Joffre, C. & Récher, C., 1 Aug 2019, In: Oncogenesis. 8, 8, 39.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Autophagy 100%
  • Acute Myeloid Leukemia 99%
  • Cell Proliferation 68%
  • Mutation 58%
  • Core Binding Factors 27%
  20 Citations (Scopus)

• Targeting epigenetic pathways in the treatment of recurrent high-grade glioma

  Hau, A., Houben, L., Klein, E., Oudin, A., Stieber, D., Flies, B., Kaoma, T., Azuaje, F., Fritah, S., Bjerkvig, R., Hertel, F., Mittelbronn, M., Golebiewska, A. & Niclou, S. P., Aug 2019, p. 22-22.

  Research output: Contribution to conference › Abstract › peer-review
• 2018

  Inhibition of HIF1α-dependent upregulation of phospho-L-Plastin resensitizes multiple myeloma cells to frontline therapy

  Bosseler, M., Marani, V., Broukou, A., Lequeux, A., Kaoma, T., Schlesser, V., François, J. H., Palissot, V., Berchem, G. J., Aouali, N. & Janji, B., Jun 2018, In: International Journal of Molecular Sciences. 19, 6, 1551.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • plastin 84%
  • Phosphorylation 55%
  • drugs 51%
  • Multiple Myeloma 51%
  8 Citations (Scopus)

• Molecular characterization of glioma patient-derived orthotopic xenografts: from basic research to preclinical studies

  Hau, A-C., Golebiewska, A., Oudin, A., Houben, L., Stieber, D., Azuaje, F., Kaoma, T., Muller, A., Hertel, F., Mittelbronn, M., Bjerkvig, R. & Niclou, S., Nov 2018, p. 274-275.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach

  Tranchevent, L. C., Nazarov, P. V., Kaoma, T., Schmartz, G. P., Muller, A., Kim, S. Y., Rajapakse, J. C. & Azuaje, F., 7 Jun 2018, In: Biology Direct. 13, 1, 12.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Neuroblastoma 100%
  • Amount 42%
  • High Throughput 23%
  • Multidimensional Data 23%
  • Throughput 23%
  12 Citations (Scopus)

• Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures

  Sousa, C., Golebiewska, A., Poovathingal, S. K., Kaoma, T., Pires-Afonso, Y., Martina, S., Coowar, D., Azuaje, F., Skupin, A., Balling, R., Biber, K., Niclou, S. P. & Michelucci, A., Nov 2018, In: EMBO Reports. 19, 11, e46171.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • RNA Sequencing 100%
  • Lipopolysaccharide 66%
  • Cytometry 62%
  • Microglia 61%
  • Heterogeneity 55%
  120 Citations (Scopus)
• 2017

  Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors

  Armento, A., Ilina, E. I., Kaoma, T., Muller, A., Vallar, L., Niclou, S. P., Krüger, M. A., Mittelbronn, M. & Naumann, U., Aug 2017, In: International Journal of Oncology. 51, 2, p. 702-714 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Carboxypeptidase H 100%
  • Glioma 54%
  • Cell Movement 48%
  • Down-Regulation 20%
  • Gene Expression Profiling 15%
  9 Citations (Scopus)

• Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism

  Farge, T., Saland, E., de Toni, F., Aroua, N., Hosseini, M., Perry, R., Bosc, C., Sugita, M., Stuani, L., Fraisse, M., Scotland, S., Larrue, C., Boutzen, H., Féliu, V., Nicolau-Travers, M. L., Cassant-Sourdy, S., Broin, N., David, M., Serhan, N., Sarry, A., & 23 othersTavitian, S., Kaoma, T., Vallar, L., Iacovoni, J., Linares, L. K., Montersino, C., Castellano, R., Griessinger, E., Collette, Y., Duchamp, O., Barreira, Y., Hirsch, P., Palama, T., Gales, L., Delhommeau, F., Garmy-Susini, B. H., Portais, J. C., Vergez, F., Selak, M., Danet-Desnoyers, G., Carroll, M., Récher, C. & Sarry, J. E., Jul 2017, In: Cancer Discovery. 7, 7, p. 716-735 20 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Oxidative Phosphorylation 100%
  • Myeloid Cells 90%
  • Acute Myeloid Leukemia 84%
  • Stem Cells 65%
  • Drug Therapy 52%
  399 Citations (Scopus)

• Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia

  Gauchotte, G., Hergalant, S., Vigouroux, C., Casse, J. M., Houlgatte, R., Kaoma, T., Helle, D., Brochin, L., Rech, F., Peyre, M., Labrousse, F., Vallar, L., Guéant, J. L., Vignaud, J. M. & Battaglia-Hsu, S. F., Aug 2017, In: Journal of Pathology. 242, 4, p. 421-434 14 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • RNA-Binding Proteins 100%
  • Meningioma 93%
  • Hypoxia 68%
  • Growth 43%
  • Gene Expression Profiling 35%
  21 Citations (Scopus)

• RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

  Nazarov, P. V., Muller, A., Kaoma, T., Nicot, N., Maximo, C., Birembaut, P., Tran, N. L., Dittmar, G. & Vallar, L., 6 Jun 2017, In: BMC Genomics. 18, 1, 443.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • RNA Sequence Analysis 100%
  • Alternative Splicing 96%
  • Gene Expression Profiling 92%
  • Exons 44%
  • Long Noncoding RNA 38%
  51 Citations (Scopus)
• 2016

  Assessing cellular and circulating miRNA recovery: The impact of the RNA isolation method and the quantity of input material

  El-Khoury, V., Pierson, S., Kaoma, T., Bernardin, F. & Berchem, G., 20 Jan 2016, In: Scientific Reports. 6, 19529.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • MicroRNAs 100%
  • RNA 82%
  • Plasma Cells 23%
  • trizol 19%
  • Exosomes 13%
  124 Citations (Scopus)

• Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

  Boutzen, H., Saland, E., Larrue, C., de Toni, F., Gales, L., Castelli, F. A., Cathebas, M., Zaghdoudi, S., Stuani, L., Kaoma, T., Riscal, R., Yang, G., Hirsch, P., David, M., De Mas-Mansat, V., Delabesse, E., Vallar, L., Delhommeau, F., Jouanin, I., Ouerfelli, O., & 7 othersLe Cam, L., Linares, L. K., Junot, C., Portais, J. C., Vergez, F., Récher, C. & Sarry, J. E., 4 Apr 2016, In: Journal of Experimental Medicine. 213, 4, p. 483-497 15 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • Isocitrate Dehydrogenase 100%
  • Tretinoin 75%
  • Acute Myeloid Leukemia 69%
  • alpha-hydroxyglutarate 58%
  • Mutation 41%
  53 Citations (Scopus)

• L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway

  Lommel, M. J., Trairatphisan, P., Gäbler, K., Laurini, C., Muller, A., Kaoma, T., Vallar, L., Sauter, T. & Schaffner-Reckinger, E., Mar 2016, In: FASEB Journal. 30, 3, p. 1218-1233 16 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • plastin 100%
  • Ribosomal Protein S6 Kinases 85%
  • MAP Kinase Signaling System 67%
  • Phosphorylation 42%
  • Breast Neoplasms 39%
  27 Citations (Scopus)

• Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

  Bougnaud, S., Golebiewska, A., Oudin, A., Keunen, O., Harter, P. N., Mäder, L., Azuaje, F., Fritah, S., Stieber, D., Kaoma, T., Vallar, L., Brons, N. H. C., Daubon, T., Miletic, H., Sundstrøm, T., Herold-Mende, C., Mittelbronn, M., Bjerkvig, R. & Niclou, S. P., 31 May 2016, In: Oncotarget. 7, 22, p. 31955-31971 17 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Glioblastoma 100%
  • Brain Neoplasms 94%
  • Neoplasms 32%
  • Phenotype 27%
  • Endothelial Cells 20%
  49 Citations (Scopus)
• 2015

  An essential role of syntaxin 3 protein for granule exocytosis and secretion of il-1α, IL-1β, IL-12B, and CCL4 from differentiated HL-60 cells

  Naegelen, I., Plançon, S., Nicot, N., Kaoma, T., Muller, A., Vallar, L., Tschirhart, E. J. & Bréchard, S., 1 Mar 2015, In: Journal of Leukocyte Biology. 97, 3, p. 557-571 15 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • Qa-SNARE Proteins 100%
  • HL-60 Cells 82%
  • Exocytosis 78%
  • Interleukin-1 70%
  • Cytokines 43%
  25 Citations (Scopus)

• Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

  Sanzey, M., Abdul Rahim, S. A., Oudin, A., Dirkse, A., Kaoma, T., Vallar, L., Herold-Mende, C., Bjerkvig, R., Golebiewska, A. & Niclou, S. P., 1 May 2015, In: PLoS ONE. 10, 5, e0123544.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • glioblastoma 100%
  • Antiangiogenic 93%
  • Glioblastoma 67%
  • Intracranial 54%
  • therapeutics 53%
  76 Citations (Scopus)

• Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

  Pacheco, M. P., John, E., Kaoma, T., Heinäniemi, M., Nicot, N., Vallar, L., Bueb, J. L., Sinkkonen, L. & Sauter, T., 19 Oct 2015, In: BMC Genomics. 16, 1, 809.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Metabolic Networks and Pathways 100%
  • Epigenomics 86%
  • Macrophages 69%
  • Genes 40%
  • Chromatin Immunoprecipitation Sequencing 25%
  30 Citations (Scopus)
• 2014

  Differential effects of antofine N-oxide on solid tumor and leukemia cells

  Bour, T., Yang, X., Li, W., Bernardin, F., Kaoma, T., Muller, A., Vallar, L. & Steinmetz, A., 2014, In: Anti-Cancer Agents in Medicinal Chemistry. 14, 10, p. 1315-1323 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  • antofine 100%
  • Oxides 54%
  • Leukemia 37%
  • Neoplasms 14%
  • Vincetoxicum 12%
  4 Citations (Scopus)

• Neurodegeneration by activation of the microglial complement-phagosome pathway

  Bodea, L. G., Wang, Y., Linnartz-Gerlach, B., Kopatz, J., Sinkkonen, L., Musgrove, R., Kaoma, T., Muller, A., Vallar, L., Di Monte, D. A., Balling, R. & Neumann, H., 2014, In: Journal of Neuroscience. 34, 25, p. 8546-8556 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Phagosomes 100%
  • Complement Activation 89%
  • Dopaminergic Neurons 82%
  • Complement C3 32%
  • Substantia Nigra 28%
  147 Citations (Scopus)

• NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class i molecules

  Sleiman, M., Brons, N. H. C., Kaoma, T., Dogu, F., Villa-Forte, A., Lenoble, P., Hentges, F., Kotsch, K., Gadola, S. D., Vilches, C. & Zimmer, J., 15 Mar 2014, In: Journal of Immunology. 192, 6, p. 2602-2610 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Natural Killer Cells 100%
  • NK Cell Lectin-Like Receptor Subfamily C 22%
  • Tissue Donors 21%
  • HLA-C Antigens 19%
  • Natural Killer Cell Receptors 18%
  18 Citations (Scopus)

• The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs

  Bossis, G., Sarry, J. E., Kifagi, C., Ristic, M., Saland, E., Vergez, F., Salem, T., Boutzen, H., Baik, H., Brockly, F., Pelegrin, M., Kaoma, T., Vallar, L., Récher, C., Manenti, S. & Piechaczyk, M., 26 Jun 2014, In: Cell Reports. 7, 6, p. 1815-1823 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Myeloid Cells 100%
  • Acute Myeloid Leukemia 93%
  • Reactive Oxygen Metabolite 91%
  • Antineoplastic Agent 86%
  • Reactive Oxygen Species 78%
  70 Citations (Scopus)
• 2011

  The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray

  Moussay, E., Kaoma, T., Baginska, J., Muller, A., Van Moer, K., Nicot, N., Nazarov, P. V., Vallar, L., Chouaib, S., Berchem, G. & Janji, B., Jul 2011, In: Autophagy. 7, 7, p. 760-770 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  • Gene Expression Profiling 100%
  • Autophagy 93%
  • Breast Neoplasms 61%
  • Genes 24%
  • MCF-7 Cells 15%
  89 Citations (Scopus)