Tony Kaoma Mukendi

2024

consICA: an R package for robust reference-free deconvolution of multi-omics data

Chepeleva, M., Kaoma, T., Zinovyev, A., Toth, R. & Nazarov, P. V., 13 Jul 2024, In: Bioinformatics Advances. 4, 1, vbae102.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles

Merz, M. P., Seal, S. V., Grova, N., Mériaux, S., Guebels, P., Kanli, G., Mommaerts, E., Nicot, N., Kaoma, T., Keunen, O., Nazarov, P. V. & Turner, J. D., 11 Mar 2024, In: Scientific Reports. 14, 1, 5898.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Nosirov, B., Scafidi, A., Ermini, L., Lipsa, A., Oudin, A., Kyriakis, D., Grzyb, K., Poovathingal, S. K., Poli, A., Muller, A., Toth, R., Klink, B., Berchem, G., Berthold, C., Hertel, F. & Mittelbronn, M. & 6 others, Heiland, D. H., Skupin, A., Nazarov, P. V., Niclou, S. P., Michelucci, A. (Main author) & Golebiewska, A., 2 Apr 2024, In: Genome Medicine. 16, 1, 51.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

10 Citations (Scopus)

PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation

Lind-Holm Mogensen, F., Sousa, C., Ameli, C., Badanjak, K., Pereira, S. L., Muller, A., Kaoma, T., Coowar, D., Scafidi, A., Poovathingal, S. K., Tziortziou, M., Antony, P. M. A., Nicot, N., Ginolhac, A., Vogt Weisenhorn, D. M., Wurst, W., Poli, A., Nazarov, P. V., Skupin, A. & Grünewald, A. & 1 others, Michelucci, A., 16 Jul 2024, In: Journal of Neuroinflammation. 21, 1, 174.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

6 Citations (Scopus)

2023

Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus

Mgrditchian, T., Brown-Clay, J. (Main author), Hoffmann, C., Müller, T., Filali, L., Ockfen, E., Mao, X., Moreau, F., Casellas, C. P., Kaoma, T., Mittelbronn, M. & Thomas, C., 15 May 2023, In: Frontiers in Cell and Developmental Biology. 11, 1100938.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)

Cross-Talk between miRNAs from the Dlk1-Dio3 Locus and Histone Methylation to Protect Male Cerebellum from Methyl Donor Deficiency

Willekens, J., Mosca, P., Burt-Oberecken, N., Laugeais, E., Kaoma, T., Bernardin, F., Vallar, L., Dimofski, P., Renaud, M., Lambert, L., Leheup, B., Guéant, J. L., Leininger-Muller, B. & Dreumont, N., Nov 2023, In: Molecular Nutrition and Food Research. 67, 21, e2300040.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)

DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias

Boulanger, M., Aqrouq, M., Tempé, D., Kifagi, C., Ristic, M., Akl, D., Hallal, R., Carusi, A., Gabellier, L., De Toledo, M., Sigurdsson, J. O., Kaoma, T., Andrieu-Soler, C., Forné, T., Soler, E., Hicheri, Y., Gueret, E., Vallar, L., Olsen, J. V. & Cartron, G. & 2 others, Piechaczyk, M. & Bossis, G., 8 Sept 2023, In: Nucleic Acids Research. 51, 16, p. 8413-8433 21 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

6 Citations (Scopus)

Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Kyriakis, D., Grzyb, K., Poovathingal, S. K., Poli, A., Scafidi, A., Muller, A., Toth, R., Oudin, A., Klink, B., Berchem, G., Berthold, C., Hertel, F., Mittelbronn, M., Heiland, D. H., Skupin, A. & Nazarov, P. V. & 3 others, Niclou, S. P., Michelucci, A. (Main Author) & Golebiewska, A., 12 Dec 2023, (bioRxiv).

Research output: Working paper › Preprint

Open Access

Impact of IDH Mutations, the 1p/19q Co-Deletion and the G-CIMP Status on Alternative Splicing in Diffuse Gliomas: International Journal of Molecular Sciences

Zhang, L., Fritah, S., Nazarov, P. V., Kaoma, T. & Van Dyck, E., 6 Jun 2023, In: International Journal of Molecular Sciences. 24, 12, 9825.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)

2022

Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Yabo, Y. A., Pires-Afonso, Y., Moreno-Sanchez, P. M., Oudin, A., Kaoma, T., Nazarov, P. ,. V., Skupin, A., Niclou, S. P., Michelucci, A. & Golebiewska, A., 5 Sept 2022, In: Neuro-Oncology. 24, Suppl.2, p. ii13

Research output: Contribution to journal › Meeting Abstract › peer-review

Open Access

Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease

Garcia, P., Jürgens-Wemheuer, W., Uriarte Huarte, O., Michelucci, A., Masuch, A., Brioschi, S., Weihofen, A., Koncina, E., Coowar, D., Heurtaux, T., Glaab, E., Balling, R., Sousa, C., Kaoma, T., Nicot, N., Pfander, T., Schulz-Schaeffer, W., Allouche, A., Fischer, N. & Biber, K. & 5 others, Kleine-Borgmann, F., Mittelbronn, M., Ostaszewski, M., Schmit, K. J. & Buttini, M., May 2022, In: GLIA. 70, 5, p. 935-960 26 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

36 Citations (Scopus)

2021

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

Larrue, C., Guiraud, N., Mouchel, P. L., Dubois, M., Farge, T., Gotanègre, M., Bosc, C., Saland, E., Nicolau-Travers, M. L., Sabatier, M., Serhan, N., Sahal, A., Boet, E., Mouche, S., Heydt, Q., Aroua, N., Stuani, L., Kaoma, T., Angenendt, L. & Mikesch, J. H. & 5 others, Schliemann, C., Vergez, F., Tamburini, J., Récher, C. & Sarry, J. E., 18 Jan 2021, In: Nature Communications. 12, 1, 422.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

40 Citations (Scopus)

A New Synuclein-Transgenic Mouse Model for Early Parkinson’s Reveals Molecular Features of Preclinical Disease

Hendrickx, D. M., Garcia, P., Ashrafi, A., Sciortino, A., Schmit, K. J., Kollmus, H., Nicot, N., Kaoma, T., Vallar, L., Buttini, M. & Glaab, E., Feb 2021, In: Molecular Neurobiology. 58, 2, p. 576-602 27 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

6 Citations (Scopus)

Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers

Bejjani, F., Tolza, C., Boulanger, M., Downes, D., Romero, R., Maqbool, M. A., Zine El Aabidine, A., Andrau, J. C., Lebre, S., Brehelin, L., Parrinello, H., Rohmer, M., Kaoma, T., Vallar, L., Hughes, J. R., Zibara, K., Lecellier, C. H., Piechaczyk, M. & Jariel-Encontre, I., 18 Mar 2021, In: Nucleic Acids Research. 49, 5, p. 2488-2508 21 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

15 Citations (Scopus)

Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia

Bosc, C., Saland, E., Bousard, A., Gadaud, N., Sabatier, M., Cognet, G., Farge, T., Boet, E., Gotanègre, M., Aroua, N., Mouchel, P. L., Polley, N., Larrue, C., Kaphan, E., Picard, M., Sahal, A., Jarrou, L., Tosolini, M., Rambow, F. & Cabon, F. & 20 others, Nicot, N., Poillet-Perez, L., Wang, Y., Su, X., Fovez, Q., Kluza, J., Argüello, R. J., Mazzotti, C., Avet-Loiseau, H., Vergez, F., Tamburini, J., Fournié, J. J., Tiong, I. S., Wei, A. H., Kaoma, T., Marine, J. C., Récher, C., Stuani, L., Joffre, C. & Sarry, J. E., Nov 2021, In: Nature Cancer. 2, 11, p. 1204-1223 20 p.

Research output: Contribution to journal › Article › Research › peer-review

60 Citations (Scopus)

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

Stuani, L., Sabatier, M., Saland, E., Cognet, G., Poupin, N., Bosc, C., Castelli, F. A., Gales, L., Turtoi, E., Montersino, C., Farge, T., Boet, E., Broin, N., Larrue, C., Baran, N., Cisse, M. Y., Conti, M., Loric, S., Kaoma, T. & Hucteau, A. & 33 others, Zavoriti, A., Sahal, A., Mouchel, P. L., Gotanègre, M., Cassan, C., Fernando, L., Wang, F., Hosseini, M., Chu-Van, E., Cam, L. L., Carroll, M., Selak, M. A., Vey, N., Castellano, R., Fenaille, F., Turtoi, A., Cazals, G., Bories, P., Gibon, Y., Nicolay, B., Ronseaux, S., Marszalek, J. R., Takahashi, K., DiNardo, C. D., Konopleva, M., Pancaldi, V., Collette, Y., Bellvert, F., Jourdan, F., Linares, L. K., Recher, C., Portais, J. C. & Sarry, J. E., 3 May 2021, In: Journal of Experimental Medicine. 218, 5, e20200924.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

79 Citations (Scopus)

2020

Deconvolution of “big data” in cancer genomics: from pancancer level to single cells

Chepeleva, M., Wang, Y., Kakoichankava, A., Muller, A., Kaoma, T. & Nazarov, P. V., 9 Jul 2020, Computer Technologies and Data Analysis (CTDA'2020) : Materials of II International Scientific-Practical Conference, Minsk, 23-24 April, 2020. Bishkek, V. A. & Skakun, V. (eds.). Minsk: BSU, p. 7-11 5 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Extracellular atp and cd39 activate camp-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia

Aroua, N., Boet, E., Ghisi, M., Nicolau-Travers, M. L., Saland, E., Gwilliam, R., de Toni, F., Hosseini, M., Mouchel, P. L., Farge, T., Bosc, C., Stuani, L., Sabatier, M., Mazed, F., Larrue, C., Jarrou, L., Gandarillas, S., Bardotti, M., Picard, M. & Syrykh, C. & 13 others, Laurent, C., Gotanègre, M., Bonnefoy, N., Bellvert, F., Portais, J. C., Nicot, N., Azuaje, F., Kaoma, T., Joffre, C., Tamburini, J., Récher, C., Vergez, F. & Sarry, J. E., 2020, In: Cancer Discovery. 10, 10, p. 1544-1565 22 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

51 Citations (Scopus)

Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software

Decamps, C., Privé, F., Bacher, R., Jost, D., Waguet, A., Achard, S., Amblard, E., Bacher, R., Bergmann, F., Blum, M., Blum, Y., Bottaz-Bosson, G., Broseus, L., Chuffart, F., Decamps, C., Devijver, E., Durif, G., Feofanov, V., Houseman, E. A. & Gallopin, M. & 25 others, Jedynak, P., Jonchere, V., Van De Geer, E., Jumentier, B., Kaoma, T., Lurie, E., Lutsik, P., Markowski, J., Melnykova, A., Merlevede, J., Nazarov, P., Nguyen, N. H., Permiakova, O., Privé, F., Richard, M., Rolland, M., Scherer, M., Spill, Y., Houseman, E. A., Lurie, E., Lutsik, P., Milosavljevic, A., Scherer, M., Blum, M. G. B. & Richard, M., 13 Jan 2020, In: BMC Bioinformatics. 21, 1, 16.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

29 Citations (Scopus)

Machine learning-assisted neurotoxicity prediction in human midbrain organoids

Monzel, A. S., Hemmer, K., Kaoma, T., Smits, L. M., Bolognin, S., Lucarelli, P., Rosety, I., Zagare, A., Antony, P., Nickels, S. L., Krueger, R., Azuaje, F. & Schwamborn, J. C., Jun 2020, In: Parkinsonism and Related Disorders. 75, p. 105-109 5 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

55 Citations (Scopus)

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

Golebiewska, A., Hau, A. C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., Michelucci, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., Azuaje, F., De Falco, A., Flies, B. & Richart, L. & 21 others, Poovathingal, S., Arns, T., Grzyb, K., Mock, A., Herold-Mende, C., Steino, A., Brown, D., May, P., Miletic, H., Malta, T. M., Noushmehr, H., Kwon, Y. J., Jahn, W., Klink, B., Tanner, G., Stead, L. F., Mittelbronn, M., Skupin, A., Hertel, F., Bjerkvig, R. & Niclou, S. P., Dec 2020, In: Acta Neuropathologica. 140, 6, p. 919-949 31 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

98 Citations (Scopus)

Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz

Scherer, M., Nazarov, P. V., Toth, R., Sahay, S., Kaoma, T., Maurer, V., Vedeneev, N., Plass, C., Lengauer, T., Walter, J. & Lutsik, P., 1 Oct 2020, In: Nature Protocols. 15, 10, p. 3240-3263 24 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

25 Citations (Scopus)

2019

Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas

Zeiner, P. S., Preusse, C., Golebiewska, A., Zinke, J., Iriondo, A., Muller, A., Kaoma, T., Filipski, K., Müller-Eschner, M., Bernatz, S., Blank, A. E., Baumgarten, P., Ilina, E., Grote, A., Hansmann, M. L., Verhoff, M. A., Franz, K., Feuerhake, F., Steinbach, J. P. & Wischhusen, J. & 4 others, Stenzel, W., Niclou, S. P., Harter, P. N. & Mittelbronn, M., Jul 2019, In: Brain Pathology. 29, 4, p. 513-529 17 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

128 Citations (Scopus)

Establishing personalized treatment options for recurrent high-grade gliomas

Hau, A.-C., Houben, L., Klein, E., Oudin, A., Stieber, D., Flies, B., Kaoma, T., Azuaje, F., Fritah, S., Bjerkvig, R., Mittelbronn, M., Hertel, F., Golebiewska, A. & Niclou, S., Nov 2019, In: Neuro-Oncology. 21, Suppl.6, p. 97-98 GENE-02.

Research output: Contribution to journal › Meeting Abstract › peer-review

Open Access

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses

Azuaje, F., Kaoma Mukendi, T., Jeanty, C., Nazarov, P. V., Muller, A., Kim, S. Y., Dittmar, G., Golebiewska, A. & Niclou, S. P., 5 Mar 2019, In: F1000Research. 7, 1906.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

2 Citations (Scopus)

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia

Larrue, C., Heydt, Q., Saland, E., Boutzen, H., Kaoma, T., Sarry, J. E., Joffre, C. & Récher, C., 1 Aug 2019, In: Oncogenesis. 8, 8, 39.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

28 Citations (Scopus)

Targeting epigenetic pathways in the treatment of recurrent high-grade glioma

Hau, A., Houben, L., Klein, E., Oudin, A., Stieber, D., Flies, B., Kaoma, T., Azuaje, F., Fritah, S., Bjerkvig, R., Hertel, F., Mittelbronn, M., Golebiewska, A. & Niclou, S. P., Aug 2019, In: Neuro-Oncology. 21, Suppl.3, p. 22-22 OS12.2.

Research output: Contribution to journal › Meeting Abstract › peer-review

2018

Inhibition of HIF1α-dependent upregulation of phospho-L-Plastin resensitizes multiple myeloma cells to frontline therapy

Bosseler, M., Marani, V., Broukou, A., Lequeux, A., Kaoma, T., Schlesser, V., François, J. H., Palissot, V., Berchem, G. J., Aouali, N. & Janji, B., Jun 2018, In: International Journal of Molecular Sciences. 19, 6, 1551.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

8 Citations (Scopus)

Molecular characterization of glioma patient-derived orthotopic xenografts: from basic research to preclinical studies

Hau, A.-C., Golebiewska, A., Oudin, A., Houben, L., Stieber, D., Azuaje, F., Kaoma, T., Muller, A., Hertel, F., Mittelbronn, M., Bjerkvig, R. & Niclou, S., Nov 2018, In: Neuro-Oncology. 20, Suppl.6, p. 274-275 TMOD-29.

Research output: Contribution to journal › Meeting Abstract › peer-review

Open Access

Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach

Tranchevent, L. C., Nazarov, P. V., Kaoma, T., Schmartz, G. P., Muller, A., Kim, S. Y., Rajapakse, J. C. & Azuaje, F., 7 Jun 2018, In: Biology Direct. 13, 1, 12.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

14 Citations (Scopus)

Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures

Sousa, C., Golebiewska, A., Poovathingal, S. K., Kaoma, T., Pires-Afonso, Y., Martina, S., Coowar, D., Azuaje, F., Skupin, A., Balling, R., Biber, K., Niclou, S. P. & Michelucci, A., Nov 2018, In: EMBO Reports. 19, 11, e46171.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

198 Citations (Scopus)

2017

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors

Armento, A., Ilina, E. I., Kaoma, T., Muller, A., Vallar, L., Niclou, S. P., Krüger, M. A., Mittelbronn, M. & Naumann, U., Aug 2017, In: International Journal of Oncology. 51, 2, p. 702-714 13 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

11 Citations (Scopus)

Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism

Farge, T., Saland, E., de Toni, F., Aroua, N., Hosseini, M., Perry, R., Bosc, C., Sugita, M., Stuani, L., Fraisse, M., Scotland, S., Larrue, C., Boutzen, H., Féliu, V., Nicolau-Travers, M. L., Cassant-Sourdy, S., Broin, N., David, M., Serhan, N. & Sarry, A. & 23 others, Tavitian, S., Kaoma, T., Vallar, L., Iacovoni, J., Linares, L. K., Montersino, C., Castellano, R., Griessinger, E., Collette, Y., Duchamp, O., Barreira, Y., Hirsch, P., Palama, T., Gales, L., Delhommeau, F., Garmy-Susini, B. H., Portais, J. C., Vergez, F., Selak, M., Danet-Desnoyers, G., Carroll, M., Récher, C. & Sarry, J. E., Jul 2017, In: Cancer Discovery. 7, 7, p. 716-735 20 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

625 Citations (Scopus)

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia

Gauchotte, G., Hergalant, S., Vigouroux, C., Casse, J. M., Houlgatte, R., Kaoma, T., Helle, D., Brochin, L., Rech, F., Peyre, M., Labrousse, F., Vallar, L., Guéant, J. L., Vignaud, J. M. & Battaglia-Hsu, S. F., Aug 2017, In: Journal of Pathology. 242, 4, p. 421-434 14 p.

Research output: Contribution to journal › Article › Research › peer-review

30 Citations (Scopus)

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

Nazarov, P. V., Muller, A., Kaoma, T., Nicot, N., Maximo, C., Birembaut, P., Tran, N. L., Dittmar, G. & Vallar, L., 6 Jun 2017, In: BMC Genomics. 18, 1, 443.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

63 Citations (Scopus)

2016

Assessing cellular and circulating miRNA recovery: The impact of the RNA isolation method and the quantity of input material

El-Khoury, V., Pierson, S., Kaoma, T., Bernardin, F. & Berchem, G., 20 Jan 2016, In: Scientific Reports. 6, 19529.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

142 Citations (Scopus)

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

Boutzen, H., Saland, E., Larrue, C., de Toni, F., Gales, L., Castelli, F. A., Cathebas, M., Zaghdoudi, S., Stuani, L., Kaoma, T., Riscal, R., Yang, G., Hirsch, P., David, M., De Mas-Mansat, V., Delabesse, E., Vallar, L., Delhommeau, F., Jouanin, I. & Ouerfelli, O. & 7 others, Le Cam, L., Linares, L. K., Junot, C., Portais, J. C., Vergez, F., Récher, C. & Sarry, J. E., 4 Apr 2016, In: Journal of Experimental Medicine. 213, 4, p. 483-497 15 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

65 Citations (Scopus)

L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway

Lommel, M. J., Trairatphisan, P., Gäbler, K., Laurini, C., Muller, A., Kaoma, T., Vallar, L., Sauter, T. & Schaffner-Reckinger, E., Mar 2016, In: FASEB Journal. 30, 3, p. 1218-1233 16 p.

Research output: Contribution to journal › Article › Research › peer-review

29 Citations (Scopus)

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

Bougnaud, S., Golebiewska, A., Oudin, A., Keunen, O., Harter, P. N., Mäder, L., Azuaje, F., Fritah, S., Stieber, D., Kaoma, T., Vallar, L., Brons, N. H. C., Daubon, T., Miletic, H., Sundstrøm, T., Herold-Mende, C., Mittelbronn, M., Bjerkvig, R. & Niclou, S. P., 31 May 2016, In: Oncotarget. 7, 22, p. 31955-31971 17 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

62 Citations (Scopus)

2015

An essential role of syntaxin 3 protein for granule exocytosis and secretion of il-1α, IL-1β, IL-12B, and CCL4 from differentiated HL-60 cells

Naegelen, I., Plançon, S., Nicot, N., Kaoma, T., Muller, A., Vallar, L., Tschirhart, E. J. & Bréchard, S., 1 Mar 2015, In: Journal of Leukocyte Biology. 97, 3, p. 557-571 15 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

28 Citations (Scopus)

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

Sanzey, M., Abdul Rahim, S. A., Oudin, A., Dirkse, A., Kaoma, T., Vallar, L., Herold-Mende, C., Bjerkvig, R., Golebiewska, A. & Niclou, S. P., 1 May 2015, In: PLoS ONE. 10, 5, e0123544.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

99 Citations (Scopus)

Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

Pacheco, M. P., John, E., Kaoma, T., Heinäniemi, M., Nicot, N., Vallar, L., Bueb, J. L., Sinkkonen, L. & Sauter, T., 19 Oct 2015, In: BMC Genomics. 16, 1, 809.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

34 Citations (Scopus)

2014

Differential effects of antofine N-oxide on solid tumor and leukemia cells

Bour, T., Yang, X., Li, W., Bernardin, F., Kaoma, T., Muller, A., Vallar, L. & Steinmetz, A., 2014, In: Anti-Cancer Agents in Medicinal Chemistry. 14, 10, p. 1315-1323 9 p.

Research output: Contribution to journal › Article › Research › peer-review

7 Citations (Scopus)

Neurodegeneration by activation of the microglial complement-phagosome pathway

Bodea, L. G., Wang, Y., Linnartz-Gerlach, B., Kopatz, J., Sinkkonen, L., Musgrove, R., Kaoma, T., Muller, A., Vallar, L., Di Monte, D. A., Balling, R. & Neumann, H., 2014, In: Journal of Neuroscience. 34, 25, p. 8546-8556 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

187 Citations (Scopus)

NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class i molecules

Sleiman, M., Brons, N. H. C., Kaoma, T., Dogu, F., Villa-Forte, A., Lenoble, P., Hentges, F., Kotsch, K., Gadola, S. D., Vilches, C. & Zimmer, J., 15 Mar 2014, In: Journal of Immunology. 192, 6, p. 2602-2610 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

19 Citations (Scopus)

The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs

Bossis, G., Sarry, J. E., Kifagi, C., Ristic, M., Saland, E., Vergez, F., Salem, T., Boutzen, H., Baik, H., Brockly, F., Pelegrin, M., Kaoma, T., Vallar, L., Récher, C., Manenti, S. & Piechaczyk, M., 26 Jun 2014, In: Cell Reports. 7, 6, p. 1815-1823 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

85 Citations (Scopus)

2011

The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray

Moussay, E., Kaoma, T., Baginska, J., Muller, A., Van Moer, K., Nicot, N., Nazarov, P. V., Vallar, L., Chouaib, S., Berchem, G. & Janji, B., Jul 2011, In: Autophagy. 7, 7, p. 760-770 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

103 Citations (Scopus)

Tony Kaoma Mukendi

Research output

Search results