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Projects
- 1 Active
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Postdoctoral Fellowship: Metabolic targeting of cancer metastasis
Kiweler, N. (PI) & Meiser, J. (Scientific Advisor/Mentor)
The European Association for Cancer Research
5/10/24 → 5/10/27
Project: Research
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Modulation of the ACOD1/itaconate pathway differentially affects atherosclerosis severity across genetic models and sexes
Haase, L., Belkacemi, A., Neises, L., Kiweler, N., Wesely, C., Huchzermeier, R., Bozic, M., Khakdan, A., Sánchez, M., Mary, A., Sachs, N., Winter, H., Glaab, E., Heneka, M. T., van der Vorst, E. P. C., Mittelbronn, M., Meiser, J. & Schneider, J. G., 12 Jun 2025, In: Journal of Clinical Investigation. 135, 15, 4 p., e182472.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
Green, A. C., Marttila, P., Kiweler, N., Chalkiadaki, C., Wiita, E., Cookson, V., Lesur, A., Eiden, K., Bernardin, F., Vallin, K. S. A., Borhade, S., Long, M., Ghahe, E. K., Jiménez-Alonso, J. J., Jemth, A. S., Loseva, O., Mortusewicz, O., Meyers, M., Viry, E. & Johansson, A. I. & 14 others, , 20 Apr 2023, In: Nature Metabolism. 5, 4, p. 642-659 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access29 Citations (Scopus) -
Formate Promotes Invasion and Metastasis by Activating Fatty Acid Synthesis and Matrix Metalloproteinases
Delbrouck, C., Kiweler, N., Pozdeev, V. I., Neises, L., Oudin, A., Schuster, A., d’Hérouël, A. F., Shen, R., Halder, R., Lesur, A., Ogris, C., Lorenz, N. I., Jaeger, C., Ronellenfitsch, M. W., Piraud, M., Skupin, A., Niclou, S. P., Letellier, E. & Meiser, J., 23 Jan 2023, p. 2023.01.23.525172, (bioRxiv).Research output: Working paper › Preprint
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Formate promotes invasion and metastasis in reliance on lipid metabolism
Delbrouck, C., Kiweler, N., Chen, O., Pozdeev, V. I., Haase, L., Neises, L., Oudin, A., Fouquier d'Hérouël, A., Shen, R., Schlicker, L., Halder, R., Lesur, A., Schuster, A., Lorenz, N. I., Jaeger, C., Feucherolles, M., Frache, G., Szpakowska, M., Chevigne, A. & Ronellenfitsch, M. W. & 7 others, , 26 Sept 2023, In: Cell Reports. 42, 9, 113034.Research output: Contribution to journal › Article › Research › peer-review
Open Access12 Citations (Scopus) -
The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil
Kiweler, N., Schwarz, H., Nguyen, A., Matschos, S., Mullins, C., Piée-Staffa, A., Brachetti, C., Roos, W. P., Schneider, G., Linnebacher, M., Brenner, W. & Krämer, O. H., Oct 2023, In: Cell Biology and Toxicology. 39, 5, p. 2401-2419 19 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access16 Citations (Scopus)