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Projects
- 1 Active
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Postdoctoral Fellowship: Metabolic targeting of cancer metastasis
Kiweler, N. (PI) & Meiser, J. (Scientific Advisor/Mentor)
The European Association for Cancer Research
5/10/24 → 5/10/27
Project: Research
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Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
Green, A. C., Marttila, P., Kiweler, N., Chalkiadaki, C., Wiita, E., Cookson, V., Lesur, A., Eiden, K., Bernardin, F., Vallin, K. S. A., Borhade, S., Long, M., Ghahe, E. K., Jiménez-Alonso, J. J., Jemth, A. S., Loseva, O., Mortusewicz, O., Meyers, M., Viry, E. & Johansson, A. I. & 14 others, , 20 Apr 2023, In: Nature Metabolism. 5, 4, p. 642-659 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access16 Citations (Scopus) -
Formate Promotes Invasion and Metastasis by Activating Fatty Acid Synthesis and Matrix Metalloproteinases
Delbrouck, C., Kiweler, N., Pozdeev, V. I., Neises, L., Oudin, A., Schuster, A., d’Hérouël, A. F., Shen, R., Halder, R., Lesur, A., Ogris, C., Lorenz, N. I., Jaeger, C., Ronellenfitsch, M. W., Piraud, M., Skupin, A., Niclou, S. P., Letellier, E. & Meiser, J., 23 Jan 2023, p. 2023.01.23.525172, (bioRxiv).Research output: Working paper › Preprint
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Formate promotes invasion and metastasis in reliance on lipid metabolism
Delbrouck, C., Kiweler, N., Chen, O., Pozdeev, V. I., Haase, L., Neises, L., Oudin, A., Fouquier d'Hérouël, A., Shen, R., Schlicker, L., Halder, R., Lesur, A., Schuster, A., Lorenz, N. I., Jaeger, C., Feucherolles, M., Frache, G., Szpakowska, M., Chevigne, A. & Ronellenfitsch, M. W. & 7 others, , 26 Sept 2023, In: Cell Reports. 42, 9, 113034.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil
Kiweler, N., Schwarz, H., Nguyen, A., Matschos, S., Mullins, C., Piée-Staffa, A., Brachetti, C., Roos, W. P., Schneider, G., Linnebacher, M., Brenner, W. & Krämer, O. H., Oct 2023, In: Cell Biology and Toxicology. 39, 5, p. 2401-2419 19 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Kiweler, N., Delbrouck, C., Pozdeev, V. I., Neises, L., Soriano-Baguet, L., Eiden, K., Xian, F., Benzarti, M., Haase, L., Koncina, E., Schmoetten, M., Jaeger, C., Noman, M. Z., Vazquez, A., Janji, B., Dittmar, G., Brenner, D., Letellier, E. & Meiser, J., 16 May 2022, In: Nature Communications. 13, 1, 2699.Research output: Contribution to journal › Article › Research › peer-review
Open Access24 Citations (Scopus)