Research output per year
Research output per year
- 27 results
Search results
-
2024
Creation of a pandemic memory by tracing COVID-19 infections and immunity in Luxembourg (CON-VINCE)
Tsurkalenko, O., Bulaev, D., O'Sullivan, M. P., Snoeck, C., Ghosh, S., Kolodkin, A., Rommes, B., Gawron, P., Moreno, C. V., Gomes, C. P. C., Kaysen, A., Ohnmacht, J., Schröder, V. E., Pavelka, L., Meyers, G. R., Pauly, L., Pauly, C., Hanff, A. M., Meyrath, M. & Leist, A. & 14 others, , 9 Feb 2024, In: BMC Infectious Diseases. 24, 1, 14 p., 179.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3
Zarca, A. M., Adlere, I., Viciano, C. P., Arimont-Segura, M., Meyrath, M., Simon, I. A., Bebelman, J. P., Laan, D., Custers, H. G. J., Janssen, E., Versteegh, K. L., Buzink, M. C. M. L., Nesheva, D. N., Bosma, R., de Esch, I. J. P., Vischer, H. F., Wijtmans, M., Szpakowska, M., Chevigné, A. & Hoffmann, C. & 5 others, , 14 Mar 2024, In: Molecular Pharmacology. 105, 4, p. 301-312 12 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
2023
Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs)
Dosquet, H., Neirinckx, V., Meyrath, M., Wantz, M., Haan, S., Niclou, S. P. (Main author), Szpakowska, M. (Main author) & Chevigné, A., 20 Mar 2023, In: Methods in Enzymology. 682, p. 1-16 16 p.Research output: Contribution to journal › Article › Research › peer-review
-
2022
Atypical opioid receptors: unconventional biology and therapeutic opportunities
Palmer, C. B., Meyrath, M., Canals, M., Kostenis, E., Chevigné, A. (Main author) & Szpakowska, M., May 2022, In: Pharmacology and Therapeutics. 233, 108014.Research output: Contribution to journal › Review article › peer-review
Open Access19 Citations (Scopus) -
Conolidine analogues as selective ACKR3 modulators for the treatment of cancer and cardiovascular diseases
Chevigne, A. (Inventor), Szpakowska, M. (Inventor), Namjoshi, O. A. (Inventor), Blough, B. E. (Inventor), Decker, A. M. (Inventor) & Meyrath, M. (Inventor), 30 Jun 2022, IPC No. A61K31/397; A61K31/4025; A61K31/404; A61K31/407; A61K31/439; A61K31/4439; A61K31/454; A61K31/496; A61K31/499; A61K31/551; A61P13/12; A61P17/02; A61P25/28; A61P29/00; A61P3/04; A61P31/12; A61P31/18; A61P35/00; A61P37/08; A61P9/00; A61P9/10; C07D401/06; C07D403/06; C07D403/12; C07D471/18; C07D487/04;, Patent No. WO2022136486A1, 22 Dec 2021, Priority date 22 Dec 2020, Priority No. EP20216606AResearch output: Patent
-
Nanoluciferase-based cell fusion assay for rapid and high-throughput assessment of SARS-CoV-2-neutralizing antibodies in patient samples
Meyrath, M., Szpakowska, M., Plesseria, J. M., Domingues, O., Langlet, J., Weber, B., Krüger, R., Ollert, M. (Main author) & Chevigné, A., 8 Oct 2022, In: Methods in Enzymology. 675, p. 351-381 31 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Nanoluciferase-based complementation assay for systematic profiling of GPCR–GRK interactions
Palmer, C. B., D'Uonnolo, G. (Main author), Luís, R. (Main author), Meyrath, M., Uchański, T., Chevigné, A. (Main author) & Szpakowska, M., Jun 2022, In: Methods in Cell Biology. 169, p. 309-321 13 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Nanoluciferase-based methods to monitor activation, modulation and trafficking of atypical chemokine receptors
Luís, R., D'Uonnolo, G., Palmer, C. B., Meyrath, M., Uchański, T., Wantz, M., Rogister, B., Janji, B., Chevigné, A. & Szpakowska, M., 2022, In: Methods in Cell Biology. 169, p. 279-294 16 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus) -
The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B
D'Uonnolo, G., Reynders, N. (Main author), Meyrath, M., Abboud, D., Uchanski, T., Laeremans, T., Volkman, B. F., Janji, B., Hanson, J., Szpakowska, M. (Main author) & Chevigne, A., 1 Jun 2022, In: Frontiers in Immunology. 13, 868579.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
2021
Cxcl10 is an agonist of the cc family chemokine scavenger receptor ackr2/d6
Chevigné, A., Janji, B., Meyrath, M., Reynders, N., D’uonnolo, G., Uchański, T., Xiao, M., Berchem, G., Ollert, M., Kwon, Y. J., Noman, M. Z. & Szpakowska, M., 2 Mar 2021, In: Cancers. 13, 5, p. 1-13 13 p., 1054.Research output: Contribution to journal › Article › Research › peer-review
Open Access26 Citations (Scopus) -
New insights into the atypical chemokine receptor network and functions
Meyrath, M., 14 Jul 2021, University of Liege. 226 p.Research output: Types of Thesis › Doctoral Thesis
Open Access -
Proadrenomedullin N-Terminal 20 Peptides (PAMPs) Are Agonists of the Chemokine Scavenger Receptor ACKR3/CXCR7
Meyrath, M., Palmer, C. B., Reynders, N., Vanderplasschen, A., Ollert, M., Bouvier, M., Szpakowska, M. (Main author) & Chevigné, A., 9 Apr 2021, In: ACS Pharmacology and Translational Science. 4, 2, p. 813-823 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access15 Citations (Scopus) -
Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22
Meyrath, M., Reynders, N., Uchański, T., Chevigné, A. (Main author) & Szpakowska, M., Feb 2021, In: Journal of Leukocyte Biology. 109, 2, p. 373-376 4 p.Research output: Contribution to journal › Article › Research › peer-review
16 Citations (Scopus) -
The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7
Szpakowska, M., Decker, A. M., Meyrath, M., Palmer, C. B., Blough, B. E., Namjoshi, O. A. & Chevigné, A., 2 Jun 2021, In: Signal Transduction and Targeted Therapy. 6, 1, p. 209 209.Research output: Contribution to journal › Letter › peer-review
Open Access16 Citations (Scopus) -
2020
Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds
Wouters, E., Walraed, J., Robertson, M. J., Meyrath, M., Szpakowska, M., Chevigné, A., Skiniotis, G. & Stove, C., 10 Apr 2020, In: ACS Pharmacology and Translational Science. 3, 2, p. 285-295 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access43 Citations (Scopus) -
CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems
Kouzeli, A., Collins, P. J., Metzemaekers, M., Meyrath, M., Szpakowska, M., Artinger, M., Struyf, S., Proost, P., Chevigne, A., Legler, D. F., Eberl, M. & Moser, B., 5 Oct 2020, In: Frontiers in Immunology. 11, 561404.Research output: Contribution to journal › Article › Research › peer-review
Open Access21 Citations (Scopus) -
Novel selective ACKR3 modulators and uses thereof
Chevigne, A. (Inventor), Meyrath, M. (Inventor) & Szpakowska, M. (Inventor), 12 Nov 2020, IPC No. A61K38/00; A61K47/62; A61K47/64; A61K48/00; C07K7/08; C12N15/86; G01N33/58, Patent No. WO 2020/225070A1, 30 Apr 2020, Priority date 3 May 2019, Priority No. EP19172560AResearch output: Patent
Open Access -
The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
Meyrath, M., Szpakowska, M. (Main author), Zeiner, J., Massotte, L., Merz, M. P., Benkel, T., Simon, K., Ohnmacht, J., Turner, J. D., Krüger, R., Seutin, V., Ollert, M., Kostenis, E. & Chevigné, A., 1 Dec 2020, In: Nature Communications. 11, 1, 3033.Research output: Contribution to journal › Article › Research › peer-review
Open Access73 Citations (Scopus) -
The diverse and complex roles of atypical chemokine receptors in cancer: From molecular biology to clinical relevance and therapy
Sjöberg, E., Meyrath, M., Chevigné, A., Östman, A., Augsten, M. & Szpakowska, M., 2020, GPCR Signaling in Cancer. Academic Press Inc., p. 99-138 40 p. (Advances in Cancer Research; vol. 145).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
24 Citations (Scopus) -
2019
A novel ACKR2-Dependent role of fibroblast-derived CXCL14 in epithelial-to-mesenchymal transition and metastasis of breast cancer
Sjöberg, E., Meyrath, M., Milde, L., Herrera, M., Lövrot, J., Hägerstrand, D., Frings, O., Bartish, M., Rolny, C., Sonnhammer, E., Chevigné, A., Augsten, M. & Östman, A., 15 Jun 2019, In: Clinical Cancer Research. 25, 12, p. 3702-3717 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access82 Citations (Scopus) -
The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma
Neirinckx, V., Hau, A. C., Schuster, A., Fritah, S., Tiemann, K., Klein, E., Nazarov, P. V., Matagne, A., Szpakowska, M., Meyrath, M., Chevigné, A., Schmidt, M. H. H. & Niclou, S. P., 6 Sept 2019, In: Neuro-Oncology Advances. 1, 1, p. vdz024 vdz024.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
2018
Characterization of a threonine-rich cluster in hepatitis C virus nonstructural protein 5A and its contribution to hyperphosphorylation
Schenk, C., Meyrath, M., Warnken, U., Schnölzer, M., Mier, W., Harak, C. & Lohmann, V., 1 Dec 2018, In: Journal of Virology. 92, 24, e0073718.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3
Szpakowska, M., Nevins, A. M., Meyrath, M., Rhainds, D., D'huys, T., Guité-Vinet, F., Dupuis, N., Gauthier, P. A., Counson, M., Kleist, A., St-Onge, G., Hanson, J., Schols, D., Volkman, B. F., Heveker, N. & Chevigné, A., May 2018, In: British Journal of Pharmacology. 175, 9, p. 1419-1438 20 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access51 Citations (Scopus) -
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists
Szpakowska, M., Meyrath, M., Reynders, N., Counson, M., Hanson, J., Steyaert, J. & Chevigné, A., Jul 2018, In: Biochemical Pharmacology. 153, p. 299-309 11 p.Research output: Contribution to journal › Article › Research › peer-review
29 Citations (Scopus) -
2017
Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
Harak, C., Meyrath, M., Romero-Brey, I., Schenk, C., Gondeau, C., Schult, P., Esser-Nobis, K., Saeed, M., Neddermann, P., Schnitzler, P., Gotthardt, D., Perez-Del-Pulgar, S., Neumann-Haefelin, C., Thimme, R., Meuleman, P., Florian, W. R. V., De Francesco, R., Rice, C. M., Bartenschlager, R. & Lohmann, V., 23 Jan 2017, In: Nature Microbiology. 2, p. 17012 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
2016
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
Harak, C., Meyrath, M., Romero-Brey, I., Schenk, C., Gondeau, C., Schult, P., Esser-Nobis, K., Saeed, M., Neddermann, P., Schnitzler, P., Gotthardt, D., Perez-Del-Pulgar, S., Neumann-Haefelin, C., Thimme, R., Meuleman, P., Vondran, F. W. R., Francesco, R. D., Rice, C. M., Bartenschlager, R. & Lohmann, V., 19 Dec 2016, In: Nature Microbiology. 2, 16247.Research output: Contribution to journal › Article › Research › peer-review
51 Citations (Scopus) -
2014
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites
Bellanca, S., Summers, R. L., Meyrath, M., Dave, A., Nash, M. N., Dittmer, M., Sanchez, C. P., Stein, W. D., Martin, R. E. & Lanzer, M., 26 Dec 2014, In: Journal of Biological Chemistry. 289, 52, p. 36336-36351 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access31 Citations (Scopus)