Projects per year
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Dive into the research topics where Manuel Counson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 1 Finished
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MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes
Chevigne, A. (PI), Uchanski, T. (CoPI) & Counson, M. (Partner)
FNR - Fonds National de la Recherche
1/03/20 → 28/02/22
Project: Research
Research output
- 9 Article
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Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy
Bayrak, A., Szpakowska, M., Dicenta-Baunach, V., Counson, M., Rasch, A., Rohlfing, A. K., Chevigné, A., Gawaz, M., Laufer, S. A. & Pillaiyar, T., 22 Aug 2024, In: Journal of Medicinal Chemistry. 67, 16, p. 14553-14573 21 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Development of Mimokines, chemokine N terminus-based CXCR4 inhibitors optimized by phage display and rational design
Fievez, V., Szpakowska, M., Mosbah, A., Arumugam, K., Mathu, J., Counson, M., Beaupain, N., Seguin-Devaux, C., Deroo, S., Baudy-Floc'h, M. & Chevigné, A., Aug 2018, In: Journal of Leukocyte Biology. 104, 2, p. 343-357 15 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3
Szpakowska, M., Nevins, A. M., Meyrath, M., Rhainds, D., D'huys, T., Guité-Vinet, F., Dupuis, N., Gauthier, P. A., Counson, M., Kleist, A., St-Onge, G., Hanson, J., Schols, D., Volkman, B. F., Heveker, N. & Chevigné, A., May 2018, In: British Journal of Pharmacology. 175, 9, p. 1419-1438 20 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access51 Citations (Scopus) -
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists
Szpakowska, M., Meyrath, M., Reynders, N., Counson, M., Hanson, J., Steyaert, J. & Chevigné, A., Jul 2018, In: Biochemical Pharmacology. 153, p. 299-309 11 p.Research output: Contribution to journal › Article › Research › peer-review
29 Citations (Scopus) -
Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7
Szpakowska, M., Dupuis, N., Baragli, A., Counson, M., Hanson, J., Piette, J. & Chevigné, A., 15 Aug 2016, In: Biochemical Pharmacology. 114, p. 14-21 8 p.Research output: Contribution to journal › Article › Research › peer-review
35 Citations (Scopus)