Personal profile
Education/Academic qualification
PhD, Université de Bourgogne
Oct 2005 → Sept 2009
Master, Université de Bourgogne
Oct 2003 → Sept 2005
ADR, University of Luxembourg
May 2018 → …
External positions
PhD candidate
2004 → 2009
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Collaborations and top research areas from the last five years
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CAMEL: The one-carbon metabolism as novel therapeutic target in leukemia/lymphoma
Paggetti, J. (PI), Meiser, J. (CoPI), Viry, E. (Partner), Marttila, P. (Partner) & Pierson, S. (Partner)
1/07/25 → 30/09/28
Project: Research
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T3L2: Translation as novel therapeutic target in leukemia/lymphoma
Moussay, E. (PI) & Paggetti, J. (Partner)
1/05/24 → 31/07/27
Project: Research
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CANBIO2 (Lucie Rospape): Bioengineered small extracellular vesicles (sEV) as new cancer immunotherapies to counteract immune suppression
Paggetti, J. (PI) & Rospape, L. (PhD Student)
FNR - Fonds National de la Recherche
1/10/23 → 30/09/27
Project: Research
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I2TRON Vanessa Klapp: Immunotherapies and drug screening in improved patient-derived models: a translational approach towards personalized treatments for leukaemia
Paggetti, J. (PI), Klapp, V. (PhD Student) & Moussay, E. (CoPI)
FNR - Fonds National de la Recherche
1/09/22 → 30/08/26
Project: Research
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TNT2-CLL: Translation as Novel Therapeutic Target in CLL
Paggetti, J. (PI), Moussay, E. (CoPI) & Bauer, M. (Partner)
1/06/24 → 31/05/26
Project: Research
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Functional cooperation between the B-cell receptor and NOTCH1 in regulating metabolic reprogramming in chronic lymphocytic leukemia
Fascì, A., Vallone, F. E., Nabelsi, N., Viry, E., Sana, I., Morabito, A., Seghezzi, S., Pesce, N. A., Rovere, M., Bertola, N., Duculty, C., Ravera, S., Mouhssine, S., Muzio, M., Ghia, P., Vitale, C., Coscia, M., Moussay, E., Gaidano, G. & Allan, J. & 4 others, , May 2026, In: Leukemia. 40, 5, p. 982-995 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia
Clayfield, L., Malik, D., Whittle, J., Xu, J., Mevel, R., Fadlullah, M. Z. H., Patel, R., Szpakowska, M., Maqbool, M. A., Jones, M., Lie-A-Ling, M., Chevigne, A., Paggetti, J., Moussay, E., Baker, S. M., Iqbal, M., Maire, P., Somervaille, T. C. P., Ford, H. L. & Kouskoff, V. & 2 others, , 24 Feb 2026, In: Cell Reports. 45, 2, 30 p., 116875.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Increased LEF1 protein levels and isoform switching drive cell proliferation in chronic lymphocytic leukemia
Mateos-Jaimez, J., Vidal-Crespo, A., Charalampopoulou, S., Pérez, R. F., Chapaprieta, V., Jiménez-Martínez, V., Caviedes-Cárdenas, L., Duran-Ferrer, M., Espadas, G., Sabidó, E., Largeot, A., Herbst, S. A., Dietrich, S., Boente, M. B., Alcoceba, M., Nadeu, F., Ringshausen, I., Paggetti, J., Moussay, E. & Colomer, D. & 3 others, , 25 Dec 2025, In: Blood. 146, 26, p. 3213-3227 15 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target
Llaó-Cid, L., Wong, J., Fernandez Botana, I., Paul, Y., Wierz, M., Pilger, L.-M., Floerchinger, A., Tan, C. L., Gonder, S., Pagano, G., Chazotte, M., Bestak, K., Schifflers, C., Iskar, M., Roider, T., Czernilofsky, F., Bruch, P.-M., Mallm, J. P., Cosma, A. & Campton, D. E. & 12 others, , 7 Aug 2025, In: Nature Communications. 16, 1, 22 p., 7271.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Restoring NK Cell Cytotoxicity Post-Cryopreservation via Synthetic Cells
Zhou, X., Zhang, S., Yang, W., Gonder, S., Sadjadi, Z., Piernitzki, N., Moter, A., Sharma, S., Largeot, A., Küchler, N., Kaschek, L., Schäfer, G., Schwarz, E. C., Eichler, H., Ullrich, E., Rieger, H., Staufer, O., Paggetti, J., Moussay, E. & Hoth, M. & 1 others, , Nov 2025, In: Advanced Science. 12, 42, 16 p., e05731.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus)