Projects per year
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Dr Anna Golebiewska is Group leader of the NORLUX Neuro-Oncology laboratory at the Department of Oncology, Luxembourg Institute of Health. She has a background in molecular and cellular biology and obtained her PhD in stem cell research. Her work focuses on understanding brain tumour biology and development of clinically relevant animal models. She is particularly interested in the various aspects of tumour heterogeneity and the cancer stem cell hypothesis. Her current projects aim to tackle intrinsic plasticity allowing brain tumour cells to adapt and survive external pressures from microenvironmental cues and treatment. Her lab developed a large collection of glioma patient-derived organoids and orthotopic xenografts for preclinical research and drug testing.
Education/Academic qualification
ADR, University of Luxembourg
Award Date: 26 Mar 2018
PhD, Ph.D. in Stem Cell Biology, University of Newcastle upon Tyne
1 Oct 2005 → 30 Sept 2008
Award Date: 9 Jun 2009
Master, M.Sc. in Molecular Biology, University of Wrocław
1 Oct 2003 → 31 Aug 2005
Award Date: 14 Sept 2005
Bachelor, B.Sc. in Biotechnology, University of Wrocław
1 Oct 2000 → 1 Jul 2003
Award Date: 4 Jul 2003
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EPIPHARM: IMPACT OF EPITRANSCRIPTOMIC REGULATION ON RESPONSE TO PHARMACOLOGICAL TREATMENTS IN GLIOMAS
Golebiewska, A., Fritah, S. & Niclou, S.
1/10/22 → 30/09/24
Project: Research
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DIOMEDES: Deconvolution of heterogeneity in the Glioblastoma cellular ecosystem for understanding treatment resistance and improving patient stratification
Golebiewska, A., Nazarov, P., Mittelbronn, M., Skupin, A., Zinovyev, A., Bjerkvig, R., Brown, D., Lukashiv, T., Nosirov, B. & Dording, C.
FNR - Fonds National de la Recherche, Fondation Cancer
1/07/22 → 30/06/25
Project: Research
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RNA Therapeutic: In search of RNA Therapeutic Drugs in Oncology
Fritah, S., Golebiewska, A. & Adiamah, M.
1/03/22 → 28/02/24
Project: Research
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GLASS-LUX: Glioma Longitudinal AnalySiS in Luxembourg (GLASS-LUX): ex vivo and in vivo Functional Profiling of Recurrent Gliomas
Golebiewska, A., Niclou, S., Kwon, Y., Nazarov, P., Klink, B. & Krokhmal, I.
Collaboration Fondation Cancer - FNR , FNR - Fonds National de la Recherche
1/06/21 → 31/12/25
Project: Research
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Advancing preclinical cancer models to assess clinically relevant outcomes
Golebiewska, A. & Fields, R. C., 10 Mar 2023, In: BMC Cancer. 23, 1, 230.Research output: Contribution to journal › Editorial
Open Access -
Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Kyriakis, D., Grzyb, K., Poovathingal, S. K., Poli, A., Scafidi, A., Muller, A., Toth, R., Oudin, A., Klink, B., Berchem, G., Berthold, C., Hertel, F., Mittelbronn, M., Heiland, D. H., Skupin, A., Nazarov, P. V., & 3 others, 6 Mar 2023, (bioRxiv).Research output: Working paper › Preprint
Open Access -
How to move a ''fried egg'' - membrane blebbing in oligodendrogliomas
Niclou, S. P. & Golebiewska, A., 14 Feb 2023, (E-pub ahead of print) In: Neuro-Oncology.Research output: Contribution to journal › Article › Research › peer-review
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Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model
Zhang, Y., Wang, J., Ghobadi, S. N., Zhou, H., Huang, A., Gerosa, M., Hou, Q., Keunen, O., Golebiewska, A., Habte, F. G., Grant, G. A., Paulmurugan, R., Lee, K. S. & Wintermark, M., May 2023, In: Ultrasound in Medicine and Biology. 49, 5, p. 1082-1090 9 p.Research output: Contribution to journal › Article › Research › peer-review
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Stabilization of Stochastic Dynamical Systems of a Random Structure with Markov Switches and Poisson Perturbations
Lukashiv, T., Litvinchuk, Y., Malyk, I. V., Golebiewska, A. & Nazarov, P. V., Feb 2023, In: Mathematics. 11, 3, 582.Research output: Contribution to journal › Article › Research › peer-review
Open Access