Projects per year
Personal profile
Biosketch
Agnieszka obtained her BSc degree in Biotechnology and MSc in Molecular Biotechnology at Jagiellonian University in Cracow, Poland. In her Master thesis project she worked on inflammasome activation and pyroptosis in monocyte-derived foam cells. Within the Erasmus+ Internship program, she joined Prof. Dr. Franklin group in the Institute of Innate Immunity at University of Bonn, Germany, where she focused on interactions of platelets and innate immune cells. Then, during her time in the Dioscuri Centre for Metabolic Diseases, Nencki Institute of Experimental Biology in Warsaw, Poland, she investigated the impact of platelets on insulin secretion in β cells. In 2021, Agnieszka joined the Translational and Clinical Immunology group as a PhD Student. She is focusing on mechanisms of allergen-specific immunotherapy, as well as immune profiling of patients with rare diseases. In parallel, she is developing a semi-supervised method allowing for efficient and reproducible annotation of high-dimensional cytometry datasets.
External positions
PhD Student, University of Luxembourg
15 Feb 2021 → 14 Feb 2025
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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I2TRON Agnieszka Demczuk: Modulation of cytokine pathways for allergy specific immunotherapy
Ollert, M. (PI) & Demczuk, A. (PhD Student)
FNR - Fonds National de la Recherche
1/02/21 → 31/01/25
Project: Research
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CyCadas: accelerating interactive annotation and analysis of clustered cytometry data
Hunewald, O., Demczuk, A., Longworth, J. & Ollert, M., 7 Oct 2024, In: Bioinformatics. 40, 10, btae595.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy
Hefeng, F., Pogorelov, D., Bode, S., He, X., Ramiro-Garcia, J., Hedin, F., Ammerlaan, W., Konstantinou, M., Capelle, C., Zeng, N., Poli, A., Domingues, O., Montamat, G., Hunewald, O., Cire, S., Baron, A., Longworth, J., Neuberger-Castillo, L., Revets, D. & Guyonnet, L. & 21 others, , 22 Feb 2024, (Research Square).Research output: Working paper › Preprint
Open Access -
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study
Pogorelov, D., Bode, S. F. N., He, X., Ramiro-Garcia, J., Hedin, F., Ammerlaan, W., Konstantinou, M., Capelle, C. M., Zeng, N., Poli, A., Domingues, O., Montamat, G., Hunewald, O., Ciré, S., Baron, A., Longworth, J., Demczuk, A., Bazon, M. L., Casper, I. & Klimek, L. & 24 others, , 26 Nov 2024, In: Nature Communications. 15, 1, 22 p., 10266.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes
Hawwari, I., Rossnagel, L., Rosero, N., Maasewerd, S., Vasconcelos, M. B., Jentzsch, M., Demczuk, A., Teichmann, L. L., Meffert, L., Bertheloot, D., Ribeiro, L. S., Kallabis, S., Meissner, F., Arditi, M., Atici, A. E., Noval Rivas, M. & Franklin, B. S., 12 Aug 2024, In: EMBO Molecular Medicine. 16, 8, p. 1901-1929 29 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Platelet-derived lipids promote insulin secretion of pancreatic β cells
Karwen, T., Kolczynska-Matysiak, K., Gross, C., Löffler, M. C., Friedrich, M., Loza-Valdes, A., Schmitz, W., Wit, M., Dziaczkowski, F., Belykh, A., Trujillo-Viera, J., El-Merahbi, R., Deppermann, C., Nawaz, S., Hastoy, B., Demczuk, A., Erk, M., Wieckowski, M. R., Rorsman, P. & Heinze, K. G. & 3 others, , 11 Sept 2023, In: EMBO Molecular Medicine. 15, 9, e16858.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus)