Projects per year
Organisation profile
Organisation profile
The Tumor Stroma Interactions research group is a dynamic and multinational team studying the mechanisms leading to leukemia progression with the goal to identify new prognostic markers and therapeutic targets.
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Dive into the research topics where Tumor Stroma Interactions is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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CAMEL: The one-carbon metabolism as novel therapeutic target in leukemia/lymphoma
Paggetti, J. (PI), Meiser, J. (CoPI), Viry, E. (Partner), Marttila, P. (Partner) & Pierson, S. (Partner)
1/07/25 → 30/09/28
Project: Research
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EXIT-CLL: Extracellular Vesicles as ImmunoTherapy against CLL
Moussay, E. (PI), Paggetti, J. (CoPI) & Barros, R. (Partner)
1/02/25 → 31/01/29
Project: Research
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TRANSLATE: tRNAs Modifications and Translational Reprogramming in Leukemias-Associated Treg
Paggetti, J. (PI), Moussay, E. (CoPI) & Gumustekin, O. (PhD Student)
1/10/24 → 30/09/28
Project: Research
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Functional cooperation between the B-cell receptor and NOTCH1 in regulating metabolic reprogramming in chronic lymphocytic leukemia
Fascì, A., Vallone, F. E., Nabelsi, N., Viry, E., Sana, I., Morabito, A., Seghezzi, S., Pesce, N. A., Rovere, M., Bertola, N., Duculty, C., Ravera, S., Mouhssine, S., Muzio, M., Ghia, P., Vitale, C., Coscia, M., Moussay, E., Gaidano, G. & Allan, J. & 4 others, , May 2026, In: Leukemia. 40, 5, p. 982-995 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia
Clayfield, L., Malik, D., Whittle, J., Xu, J., Mevel, R., Fadlullah, M. Z. H., Patel, R., Szpakowska, M., Maqbool, M. A., Jones, M., Lie-A-Ling, M., Chevigne, A., Paggetti, J., Moussay, E., Baker, S. M., Iqbal, M., Maire, P., Somervaille, T. C. P., Ford, H. L. & Kouskoff, V. & 2 others, , 24 Feb 2026, In: Cell Reports. 45, 2, 30 p., 116875.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Increased LEF1 protein levels and isoform switching drive cell proliferation in chronic lymphocytic leukemia
Mateos-Jaimez, J., Vidal-Crespo, A., Charalampopoulou, S., Pérez, R. F., Chapaprieta, V., Jiménez-Martínez, V., Caviedes-Cárdenas, L., Duran-Ferrer, M., Espadas, G., Sabidó, E., Largeot, A., Herbst, S. A., Dietrich, S., Boente, M. B., Alcoceba, M., Nadeu, F., Ringshausen, I., Paggetti, J., Moussay, E. & Colomer, D. & 3 others, , 25 Dec 2025, In: Blood. 146, 26, p. 3213-3227 15 p.Research output: Contribution to journal › Article › Research › peer-review