Projects per year
Organisation profile
Organisation profile
The Tumor Stroma Interactions research group is a dynamic and multinational team studying the mechanisms leading to leukemia progression with the goal to identify new prognostic markers and therapeutic targets.
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Collaborations and top research areas from the last five years
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Profiles
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CAMEL: The one-carbon metabolism as novel therapeutic target in leukemia/lymphoma
Paggetti, J. (PI), Meiser, J. (CoPI), Viry, E. (Partner), Marttila, P. (Partner) & Pierson, S. (Partner)
1/07/25 → 30/09/28
Project: Research
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T3L2: Translation as novel therapeutic target in leukemia/lymphoma
Moussay, E. (PI) & Paggetti, J. (Partner)
1/05/24 → 31/07/27
Project: Research
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CANBIO2 (Lucie Rospape): Bioengineered small extracellular vesicles (sEV) as new cancer immunotherapies to counteract immune suppression
Paggetti, J. (PI) & Rospape, L. (PhD Student)
FNR - Fonds National de la Recherche
1/10/23 → 30/09/27
Project: Research
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Functional cooperation between the B-cell receptor and NOTCH1 in regulating metabolic reprogramming in chronic lymphocytic leukemia
Fascì, A., Vallone, F. E., Nabelsi, N., Viry, E., Sana, I., Morabito, A., Seghezzi, S., Pesce, N. A., Rovere, M., Bertola, N., Duculty, C., Ravera, S., Mouhssine, S., Muzio, M., Ghia, P., Vitale, C., Coscia, M., Moussay, E., Gaidano, G. & Allan, J. & 4 others, , May 2026, In: Leukemia. 40, 5, p. 982-995 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia
Clayfield, L., Malik, D., Whittle, J., Xu, J., Mevel, R., Fadlullah, M. Z. H., Patel, R., Szpakowska, M., Maqbool, M. A., Jones, M., Lie-A-Ling, M., Chevigne, A., Paggetti, J., Moussay, E., Baker, S. M., Iqbal, M., Maire, P., Somervaille, T. C. P., Ford, H. L. & Kouskoff, V. & 2 others, , 24 Feb 2026, In: Cell Reports. 45, 2, 30 p., 116875.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Increased LEF1 protein levels and isoform switching drive cell proliferation in chronic lymphocytic leukemia
Mateos-Jaimez, J., Vidal-Crespo, A., Charalampopoulou, S., Pérez, R. F., Chapaprieta, V., Jiménez-Martínez, V., Caviedes-Cárdenas, L., Duran-Ferrer, M., Espadas, G., Sabidó, E., Largeot, A., Herbst, S. A., Dietrich, S., Boente, M. B., Alcoceba, M., Nadeu, F., Ringshausen, I., Paggetti, J., Moussay, E. & Colomer, D. & 3 others, , 25 Dec 2025, In: Blood. 146, 26, p. 3213-3227 15 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus)